Differential Corticomotor Excitability Responses to Hypertonic Saline-Induced Muscle Pain in Forearm and Hand Muscles
Joint Authors
Graven-Nielsen, Thomas
Larsen, Dennis B.
Hirata, Rogerio P.
Boudreau, Shellie A.
Source
Issue
Vol. 2018, Issue 2018 (31 Dec. 2018), pp.1-9, 9 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2018-04-22
Country of Publication
Egypt
No. of Pages
9
Main Subjects
Abstract EN
Experimental muscle pain inhibits corticomotor excitability (CE) of upper limb muscles.
It is unknown if this inhibition affects overlapping muscle representations within the primary motor cortex to the same degree.
This study explored CE changes of the first dorsal interosseus (FDI) and extensor carpi radialis (ECR) muscles in response to muscle pain.
Participants (n=13) attended two sessions (≥48 hours in-between).
Hypertonic saline was injected in the ECR (session one) or the FDI (session two) muscle.
CE, assessed by transcranial magnetic stimulation (TMS) motor-evoked potentials (MEPs), was recorded at baseline, during pain, and twenty minutes postinjection together with pain intensity ratings.
Pain intensity ratings did not differ between the two pain sites (p=0.19).
In response to FDI muscle pain, the MEPs of the FDI muscle were reduced at 2 and 4 min postinjection (p≤0.03), but not after ECR muscle pain.
No significant MEP change was detected for the ECR muscle (p=0.62).
No associations between MEPs and pain intensity were found (p>0.2).
The present results indicate that the output from overlapping cortical representations of two muscles differentially adapts to acute muscle pain.
American Psychological Association (APA)
Larsen, Dennis B.& Graven-Nielsen, Thomas& Hirata, Rogerio P.& Boudreau, Shellie A.. 2018. Differential Corticomotor Excitability Responses to Hypertonic Saline-Induced Muscle Pain in Forearm and Hand Muscles. Neural Plasticity،Vol. 2018, no. 2018, pp.1-9.
https://search.emarefa.net/detail/BIM-1210365
Modern Language Association (MLA)
Larsen, Dennis B.…[et al.]. Differential Corticomotor Excitability Responses to Hypertonic Saline-Induced Muscle Pain in Forearm and Hand Muscles. Neural Plasticity No. 2018 (2018), pp.1-9.
https://search.emarefa.net/detail/BIM-1210365
American Medical Association (AMA)
Larsen, Dennis B.& Graven-Nielsen, Thomas& Hirata, Rogerio P.& Boudreau, Shellie A.. Differential Corticomotor Excitability Responses to Hypertonic Saline-Induced Muscle Pain in Forearm and Hand Muscles. Neural Plasticity. 2018. Vol. 2018, no. 2018, pp.1-9.
https://search.emarefa.net/detail/BIM-1210365
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1210365