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Maximizing the Survival of Amyotrophic Lateral Sclerosis Patients: Current Perspectives
Joint Authors
Abuzinadah, Ahmad R.
Khairoalsindi, Osama A.
Source
Neurology Research International
Issue
Vol. 2018, Issue 2018 (31 Dec. 2018), pp.1-12, 12 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2018-08-12
Country of Publication
Egypt
No. of Pages
12
Main Subjects
Abstract EN
Amyotrophic lateral sclerosis is a neurodegenerative disease that leads to loss of the upper and lower motor neurons.
Almost 90% of all cases occur in the sporadic form, with the rest occurring in the familial form.
The disease has a poor prognosis, with only two disease-modifying drugs approved by the United States Food and Drug Administration (FDA).
The approved drugs for the disease have very limited survival benefits.
Edaravone is a new FDA-approved medication that may slow the disease progression by 33% in a selected subgroup of ALS patients.
This paper covers the various interventions that may provide survival benefits, such as early diagnosis, medications, gene therapy, stem cell therapy, diet, nutritional supplements, multidisciplinary clinics, and mechanical invasive and noninvasive ventilation.
The recent data on masitinib, the role of enteral feeding, gene therapy, and stem cell therapy is discussed.
American Psychological Association (APA)
Khairoalsindi, Osama A.& Abuzinadah, Ahmad R.. 2018. Maximizing the Survival of Amyotrophic Lateral Sclerosis Patients: Current Perspectives. Neurology Research International،Vol. 2018, no. 2018, pp.1-12.
https://search.emarefa.net/detail/BIM-1210607
Modern Language Association (MLA)
Khairoalsindi, Osama A.& Abuzinadah, Ahmad R.. Maximizing the Survival of Amyotrophic Lateral Sclerosis Patients: Current Perspectives. Neurology Research International No. 2018 (2018), pp.1-12.
https://search.emarefa.net/detail/BIM-1210607
American Medical Association (AMA)
Khairoalsindi, Osama A.& Abuzinadah, Ahmad R.. Maximizing the Survival of Amyotrophic Lateral Sclerosis Patients: Current Perspectives. Neurology Research International. 2018. Vol. 2018, no. 2018, pp.1-12.
https://search.emarefa.net/detail/BIM-1210607
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1210607