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Oxidative and Antioxidative Status of Children with Celiac Disease Treated with a Gluten Free-Diet
Joint Authors
Chełchowska, Magdalena
Ambroszkiewicz, Jadwiga
Czaja-Bulsa, Grażyna
Rowicka, Grażyna
Riahi, Agnieszka
Weker, Halina
Strucińska, Małgorzata
Source
Oxidative Medicine and Cellular Longevity
Issue
Vol. 2018, Issue 2018 (31 Dec. 2018), pp.1-8, 8 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2018-05-02
Country of Publication
Egypt
No. of Pages
8
Main Subjects
Abstract EN
Aims.
Oxidative stress is a factor involved in the pathogenesis of celiac disease (CD), possibly affecting the course of the disease and celiac-related complications.
We assessed the intensity of oxidative processes and the efficiency of antioxidant defense in children with celiac disease.
Methods.
Group I (n=32) consisted of children with CD treated with a gluten-free diet, and group II (n=24) consisted of healthy children on a traditional diet.
Antioxidative and oxidative status was assessed by measurement of serum total antioxidant capacity (TAC), total oxidant capacity (TOC), and oxidized low-density lipoprotein (ox-LDL) and on the basis of oxidative stress index (OSI).
Results.
There were no significant differences in serum TAC, TOC, ox-LDL, and OSI between children with CD and healthy children.
Cluster analysis showed that the group of children with CD is not homogeneous in terms of serum TAC and TOC levels.
About 50% of these children had TAC levels < 1.3 mmol/L and TOC levels > 0.35 mmol/L.
Conclusions.
Strict adherence to a gluten-free diet by children with CD seems to be important for maintaining oxidative-antioxidant balance.
However, further research is needed to identify factors potentially responsible for increased oxidative stress in some children with celiac disease despite adherence to a gluten-free diet.
American Psychological Association (APA)
Rowicka, Grażyna& Czaja-Bulsa, Grażyna& Chełchowska, Magdalena& Riahi, Agnieszka& Strucińska, Małgorzata& Weker, Halina…[et al.]. 2018. Oxidative and Antioxidative Status of Children with Celiac Disease Treated with a Gluten Free-Diet. Oxidative Medicine and Cellular Longevity،Vol. 2018, no. 2018, pp.1-8.
https://search.emarefa.net/detail/BIM-1210854
Modern Language Association (MLA)
Rowicka, Grażyna…[et al.]. Oxidative and Antioxidative Status of Children with Celiac Disease Treated with a Gluten Free-Diet. Oxidative Medicine and Cellular Longevity No. 2018 (2018), pp.1-8.
https://search.emarefa.net/detail/BIM-1210854
American Medical Association (AMA)
Rowicka, Grażyna& Czaja-Bulsa, Grażyna& Chełchowska, Magdalena& Riahi, Agnieszka& Strucińska, Małgorzata& Weker, Halina…[et al.]. Oxidative and Antioxidative Status of Children with Celiac Disease Treated with a Gluten Free-Diet. Oxidative Medicine and Cellular Longevity. 2018. Vol. 2018, no. 2018, pp.1-8.
https://search.emarefa.net/detail/BIM-1210854
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1210854