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Assessment of the State of the Natural Antioxidant Barrier of a Body in Patients Complaining about the Presence of Tinnitus
Joint Authors
Augustyńska, Beata
Mikołajewska, Emilia
Pawlak-Osińska, Katarzyna
Kupczyk, Daria
Bilski, Rafał
Kaźmierczak, Henryk
Marzec, Maria
Mikołajewski, Dariusz
Source
Oxidative Medicine and Cellular Longevity
Issue
Vol. 2018, Issue 2018 (31 Dec. 2018), pp.1-8, 8 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2018-10-28
Country of Publication
Egypt
No. of Pages
8
Main Subjects
Abstract EN
Background.
Tinnitus is defined as a phantom auditory perception, i.e., sound experience despite the lack of acoustic stimuli in the environment.
The aim of this study was to assess the state of the natural antioxidant barrier of a body in patients complaining about the presence of tinnitus.
Material and Methods.
The study included a total of 51 patients aged from 20 to 62 years with diagnosed idiopathic tinnitus and 19 healthy subjects as a control group.
All patients underwent the audiometric tone test, speech audiometry, distortion otoacoustic emission product testing, study of evoked auditory potentials of short latency, and biochemical analysis of venous blood concerning values of activity or concentration of glutathione, glutathione peroxidase, S-transferase, glutathione reductase superoxide dismutase, malondialdehyde, and ceruloplasmin as the selected parameters of oxidative stress.
Results.
Disorders of the auditory pathway were not only limited to the cochlea but also covered its further episodes.
Mean values of activity or concentration of the selected parameters of oxidative stress in the study and control groups showed reduced effectiveness of the body’s natural antioxidant barrier.
Discussion.
Patients complaining about the presence of tinnitus showed reduced effectiveness of the body’s natural antioxidant barrier compared to the control group.
Conclusions.
The main indication to undertake further research on the functioning of the antioxidant barrier in people suffering from ailments in the form of tinnitus is to determine a suitable therapy aimed at improving the quality of life of these patients, which might be the administration of antioxidant medications.
American Psychological Association (APA)
Pawlak-Osińska, Katarzyna& Kaźmierczak, Henryk& Marzec, Maria& Kupczyk, Daria& Bilski, Rafał& Mikołajewska, Emilia…[et al.]. 2018. Assessment of the State of the Natural Antioxidant Barrier of a Body in Patients Complaining about the Presence of Tinnitus. Oxidative Medicine and Cellular Longevity،Vol. 2018, no. 2018, pp.1-8.
https://search.emarefa.net/detail/BIM-1210877
Modern Language Association (MLA)
Pawlak-Osińska, Katarzyna…[et al.]. Assessment of the State of the Natural Antioxidant Barrier of a Body in Patients Complaining about the Presence of Tinnitus. Oxidative Medicine and Cellular Longevity No. 2018 (2018), pp.1-8.
https://search.emarefa.net/detail/BIM-1210877
American Medical Association (AMA)
Pawlak-Osińska, Katarzyna& Kaźmierczak, Henryk& Marzec, Maria& Kupczyk, Daria& Bilski, Rafał& Mikołajewska, Emilia…[et al.]. Assessment of the State of the Natural Antioxidant Barrier of a Body in Patients Complaining about the Presence of Tinnitus. Oxidative Medicine and Cellular Longevity. 2018. Vol. 2018, no. 2018, pp.1-8.
https://search.emarefa.net/detail/BIM-1210877
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1210877