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Influence of Diosmin Treatment on the Level of Oxidative Stress Markers in Patients with Chronic Venous Insufficiency
Joint Authors
Feldo, Marcin
Sowa, Ireneusz
Bogucka-Kocka, Anna
Wójciak-Kosior, Magdalena
Bogucki, Jacek
Woźniak, Michał
Kot-Waśik, Agata
Aszyk, Justyna
Zubilewicz, Tomasz
Source
Oxidative Medicine and Cellular Longevity
Issue
Vol. 2018, Issue 2018 (31 Dec. 2018), pp.1-5, 5 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2018-08-28
Country of Publication
Egypt
No. of Pages
5
Main Subjects
Abstract EN
Oxidative stress plays an important role in the pathophysiology of many human disorders, while antioxidants prevent the development of various adverse symptoms.
Diosmin is a natural flavonoid applied in vascular system disorders, especially in chronic venous insufficiency (CVI), and it plays a significant part in the alleviation of CVI symptoms.
Due to antioxidant activity, it also has the ability to scavenge the oxygen free radicals and hence decreases the level of oxidative stress biomarkers, such as prostaglandins and their precursors—isoprostanes.
In the study, the influence of diosmin treatment on the level of isoprostanes in plasma samples of patients suffering from CVI was examined.
The qualitative analysis was performed using high-performance liquid chromatography with spectrometry detection (LC-MS).
The statistically significant decrease of isoprostane content after 3 months of treatment was observed within the studied group; however, the most significant changes were observed in patients who smoke.
American Psychological Association (APA)
Feldo, Marcin& Woźniak, Michał& Wójciak-Kosior, Magdalena& Sowa, Ireneusz& Kot-Waśik, Agata& Aszyk, Justyna…[et al.]. 2018. Influence of Diosmin Treatment on the Level of Oxidative Stress Markers in Patients with Chronic Venous Insufficiency. Oxidative Medicine and Cellular Longevity،Vol. 2018, no. 2018, pp.1-5.
https://search.emarefa.net/detail/BIM-1211063
Modern Language Association (MLA)
Feldo, Marcin…[et al.]. Influence of Diosmin Treatment on the Level of Oxidative Stress Markers in Patients with Chronic Venous Insufficiency. Oxidative Medicine and Cellular Longevity No. 2018 (2018), pp.1-5.
https://search.emarefa.net/detail/BIM-1211063
American Medical Association (AMA)
Feldo, Marcin& Woźniak, Michał& Wójciak-Kosior, Magdalena& Sowa, Ireneusz& Kot-Waśik, Agata& Aszyk, Justyna…[et al.]. Influence of Diosmin Treatment on the Level of Oxidative Stress Markers in Patients with Chronic Venous Insufficiency. Oxidative Medicine and Cellular Longevity. 2018. Vol. 2018, no. 2018, pp.1-5.
https://search.emarefa.net/detail/BIM-1211063
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1211063