Work Intensity, Low-Grade Inflammation, and Oxidative Status: A Comparison between Office and Slaughterhouse Workers
Joint Authors
Zelzer, Sieglinde
Herrmann, Markus
Tatzber, Franz
Cvirn, Gerhard
Wonisch, Willibald
Obermayer-Pietsch, Barbara
Rinnerhofer, Stefan
Kundi, Michael
Niedrist, Tobias
Wultsch, Georg
Mangge, Harald
Source
Oxidative Medicine and Cellular Longevity
Issue
Vol. 2018, Issue 2018 (31 Dec. 2018), pp.1-7, 7 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2018-04-18
Country of Publication
Egypt
No. of Pages
7
Main Subjects
Abstract EN
Limited knowledge exists about the impact of physical workload on oxidative stress in different occupational categories.
Thus, we aimed to investigate the oxidative and inflammatory status in employees with different physical workloads.
We enrolled a total of 79 male subjects, 27 office workers (mean age 38.8 ± 9.1 years) and 52 heavy workers, in a slaughterhouse (mean age 40.8 ± 8.2 years).
Fasting blood was drawn from an antecubital vein in the morning of the midweek before an 8-hour or 12-hour work shift.
The antioxidative capacity was assessed measuring total antioxidant capacity (TAC), uric acid, total polyphenols (PPm), and endogenous peroxidase activity (EPA).
Total peroxides (TOC), malondialdehyde (MDA), and myeloperoxidase (MPO) were analyzed as prooxidative biomarkers, and an oxidative stress index (OSI) was calculated.
In addition, hsCRP, interleukin-6 (IL-6), MDA-LDL IgM antibodies, galectin-3, adrenocorticotropic hormone (ACTH), and the brain-derived neurotrophic factor (BDNF) were measured as biomarkers of chronic systemic inflammation and emotional stress.
TOC (p=0.032), TAC (p<0.001), ACTH (p<0.001), OSI (p=0.011), and hsCRP (p=0.019) were significantly increased in the heavy workers group, while EPA, BDNF (p<0.001), and polyphenols (p=0.004) were significantly higher in office workers.
Comparison between 8 and 12 h shifts showed a worse psychological condition in heavy workers with increased levels for hsCRP (p=0.001) and reduced concentration of BDNF (p=0.012) compared to office workers.
Oxidative stress and inflammation are induced in heavy workers and are particularly pronounced during long working hours, that is, 12-hour versus 8-hour shifts.
American Psychological Association (APA)
Zelzer, Sieglinde& Tatzber, Franz& Herrmann, Markus& Wonisch, Willibald& Rinnerhofer, Stefan& Kundi, Michael…[et al.]. 2018. Work Intensity, Low-Grade Inflammation, and Oxidative Status: A Comparison between Office and Slaughterhouse Workers. Oxidative Medicine and Cellular Longevity،Vol. 2018, no. 2018, pp.1-7.
https://search.emarefa.net/detail/BIM-1211082
Modern Language Association (MLA)
Zelzer, Sieglinde…[et al.]. Work Intensity, Low-Grade Inflammation, and Oxidative Status: A Comparison between Office and Slaughterhouse Workers. Oxidative Medicine and Cellular Longevity No. 2018 (2018), pp.1-7.
https://search.emarefa.net/detail/BIM-1211082
American Medical Association (AMA)
Zelzer, Sieglinde& Tatzber, Franz& Herrmann, Markus& Wonisch, Willibald& Rinnerhofer, Stefan& Kundi, Michael…[et al.]. Work Intensity, Low-Grade Inflammation, and Oxidative Status: A Comparison between Office and Slaughterhouse Workers. Oxidative Medicine and Cellular Longevity. 2018. Vol. 2018, no. 2018, pp.1-7.
https://search.emarefa.net/detail/BIM-1211082
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1211082