Biological Activities and Potential Oral Applications of N-Acetylcysteine: Progress and Prospects
Joint Authors
Jiao, Yang
Tay, Franklin R.
Liu, Huan
Chen, Ji-hua
Pei, Yanping
Yang, Yi
Yang, Yanwei
Source
Oxidative Medicine and Cellular Longevity
Issue
Vol. 2018, Issue 2018 (31 Dec. 2018), pp.1-14, 14 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2018-04-22
Country of Publication
Egypt
No. of Pages
14
Main Subjects
Abstract EN
N-Acetylcysteine (NAC), a cysteine prodrug and glutathione (GSH) precursor, has been used for several decades in clinical therapeutic practices as a mucolytic agent and for the treatment of disorders associated with GSH deficiency.
Other therapeutic activities of NAC include inhibition of inflammation/NF-κB signaling and expression of proinflammatory cytokines.
N-Acetylcysteine is also a nonantibiotic compound possessing antimicrobial property and exerts anticarcinogenic and antimutagenic effects against certain types of cancer.
Recently, studies describing potentially important biological and pharmacological activities of NAC have stimulated interests in using NAC-based therapeutics for oral health care.
The present review focused on the biological activities of NAC and its potential oral applications.
The potential side effects of NAC and formulations for drug delivery were also discussed, with the intent of advancing NAC-associated treatment modalities in oral medicine.
American Psychological Association (APA)
Pei, Yanping& Liu, Huan& Yang, Yi& Yang, Yanwei& Jiao, Yang& Tay, Franklin R.…[et al.]. 2018. Biological Activities and Potential Oral Applications of N-Acetylcysteine: Progress and Prospects. Oxidative Medicine and Cellular Longevity،Vol. 2018, no. 2018, pp.1-14.
https://search.emarefa.net/detail/BIM-1211102
Modern Language Association (MLA)
Pei, Yanping…[et al.]. Biological Activities and Potential Oral Applications of N-Acetylcysteine: Progress and Prospects. Oxidative Medicine and Cellular Longevity No. 2018 (2018), pp.1-14.
https://search.emarefa.net/detail/BIM-1211102
American Medical Association (AMA)
Pei, Yanping& Liu, Huan& Yang, Yi& Yang, Yanwei& Jiao, Yang& Tay, Franklin R.…[et al.]. Biological Activities and Potential Oral Applications of N-Acetylcysteine: Progress and Prospects. Oxidative Medicine and Cellular Longevity. 2018. Vol. 2018, no. 2018, pp.1-14.
https://search.emarefa.net/detail/BIM-1211102
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1211102