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Biological Effects of Tetrahydroxystilbene Glucoside: An Active Component of a Rhizome Extracted from Polygonum multiflorum
Joint Authors
Source
Oxidative Medicine and Cellular Longevity
Issue
Vol. 2018, Issue 2018 (31 Dec. 2018), pp.1-15, 15 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2018-11-04
Country of Publication
Egypt
No. of Pages
15
Main Subjects
Abstract EN
Polygonum multiflorum Thunb.
(PM), a traditional Chinese medicinal herb, has been widely used in the Orient as a tonic and antiaging agent.
2,3,5,4′-Tetrahydroxystilbene-2-O-β-D-glucoside (TSG, C20H22O9, FW = 406.38928) is one of the active components extracted from PM.
TSG is an antioxidant agent, which exhibits remarkable antioxidative activities in vivo and in vitro.
The antioxidant effect of TSG is achieved by its radical-scavenging effects.
TSG can inhibit apoptosis and protect neuronal cells against injury through multifunctional cytoprotective pathways.
TSG performs prophylactic and therapeutic activities against Alzheimer’s disease, Parkinson’s disease, and cerebral ischemia/reperfusion injury.
It is also antiatherosclerotic and anti-inflammatory.
However, the mechanisms underlying these pharmacological activities are unclear.
This study aimed at reviewing experimental studies and describing the effectiveness and possible mechanisms of TSG.
American Psychological Association (APA)
Zhang, Lingling& Chen, Jianzong. 2018. Biological Effects of Tetrahydroxystilbene Glucoside: An Active Component of a Rhizome Extracted from Polygonum multiflorum. Oxidative Medicine and Cellular Longevity،Vol. 2018, no. 2018, pp.1-15.
https://search.emarefa.net/detail/BIM-1211279
Modern Language Association (MLA)
Zhang, Lingling& Chen, Jianzong. Biological Effects of Tetrahydroxystilbene Glucoside: An Active Component of a Rhizome Extracted from Polygonum multiflorum. Oxidative Medicine and Cellular Longevity No. 2018 (2018), pp.1-15.
https://search.emarefa.net/detail/BIM-1211279
American Medical Association (AMA)
Zhang, Lingling& Chen, Jianzong. Biological Effects of Tetrahydroxystilbene Glucoside: An Active Component of a Rhizome Extracted from Polygonum multiflorum. Oxidative Medicine and Cellular Longevity. 2018. Vol. 2018, no. 2018, pp.1-15.
https://search.emarefa.net/detail/BIM-1211279
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1211279