Antioxidant Status in the Soleus Muscle of Sprague-Dawley Rats in Relation to Duodenal-Jejunal Omega Switch and Different Dietary Patterns
Joint Authors
Romuk, Ewa
Skrzep-Poloczek, Bronisława
Stygar, Dominika
Chełmecka, Elżbieta
Sawczyn, Tomasz
Karcz, Konrad Wojciech
Nabrdalik, Katarzyna
Gumprecht, Janusz
Poloczek, Jakub
Source
Oxidative Medicine and Cellular Longevity
Issue
Vol. 2018, Issue 2018 (31 Dec. 2018), pp.1-12, 12 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2018-07-08
Country of Publication
Egypt
No. of Pages
12
Main Subjects
Abstract EN
Background.
Obesity and chronic ingestion of lipid-rich meals are related to an enhanced oxidative stress (OS).
Aims.
To examine the influence of duodenal-jejunal omega switch surgery in combination with different diets on the antioxidative status in the soleus muscle of rats.
Methods.
After 8 weeks on a high-fat diet (HF) or control diet (CD), rats underwent duodenal-jejunal omega switch (DJOS) or SHAM (control) surgery.
After surgery, for the next 8 weeks, half of DJOS/SHAM animals were kept on the same diet as before, and half had a changed diet.
The total superoxide dismutase (SOD), catalase (CAT), glutathione peroxidase (GPx), glutathione-S-transferase (GST), and glutathione reductase (GR) activity as well as malondialdehyde (MDA) concentration were measured in the soleus of rats.
Results.
CAT and GPx activity were significantly lower after DJOS surgery versus SHAM, regardless of the type of diet.
The activity of CAT, SOD, GR, CuZnSOD, and GPx was altered in the CD/HF or HF/CD groups.
After DJOS, the lowest muscle concentration of MDA was observed in the CD/CD group and the highest in CD/HF.
Conclusions.
DJOS surgery significantly decreases the antioxidative system in soleus muscles of rats.
CD/HF and HF/CD dietary patterns lead to an increase in antioxidative activity, while remaining on unchanged diet (CD or HF) is associated with a reduced oxidative stress.
American Psychological Association (APA)
Skrzep-Poloczek, Bronisława& Stygar, Dominika& Chełmecka, Elżbieta& Nabrdalik, Katarzyna& Romuk, Ewa& Poloczek, Jakub…[et al.]. 2018. Antioxidant Status in the Soleus Muscle of Sprague-Dawley Rats in Relation to Duodenal-Jejunal Omega Switch and Different Dietary Patterns. Oxidative Medicine and Cellular Longevity،Vol. 2018, no. 2018, pp.1-12.
https://search.emarefa.net/detail/BIM-1211303
Modern Language Association (MLA)
Skrzep-Poloczek, Bronisława…[et al.]. Antioxidant Status in the Soleus Muscle of Sprague-Dawley Rats in Relation to Duodenal-Jejunal Omega Switch and Different Dietary Patterns. Oxidative Medicine and Cellular Longevity No. 2018 (2018), pp.1-12.
https://search.emarefa.net/detail/BIM-1211303
American Medical Association (AMA)
Skrzep-Poloczek, Bronisława& Stygar, Dominika& Chełmecka, Elżbieta& Nabrdalik, Katarzyna& Romuk, Ewa& Poloczek, Jakub…[et al.]. Antioxidant Status in the Soleus Muscle of Sprague-Dawley Rats in Relation to Duodenal-Jejunal Omega Switch and Different Dietary Patterns. Oxidative Medicine and Cellular Longevity. 2018. Vol. 2018, no. 2018, pp.1-12.
https://search.emarefa.net/detail/BIM-1211303
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1211303