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Pharmacological Regulation of Oxidative Stress in Stem Cells
Joint Authors
Choi, Inpyo
Jung, Haiyoung
Lee, Jungwoon
Cho, Yee Sook
Source
Oxidative Medicine and Cellular Longevity
Issue
Vol. 2018, Issue 2018 (31 Dec. 2018), pp.1-13, 13 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2018-09-30
Country of Publication
Egypt
No. of Pages
13
Main Subjects
Abstract EN
Oxidative stress results from an imbalance between reactive oxygen species (ROS) production and antioxidant defense mechanisms.
The regulation of stem cell self-renewal and differentiation is crucial for early development and tissue homeostasis.
Recent reports have suggested that the balance between self-renewal and differentiation is regulated by the cellular oxidation-reduction (redox) state; therefore, the study of ROS regulation in regenerative medicine has emerged to develop protocols for regulating appropriate stem cell differentiation and maintenance for clinical applications.
In this review, we introduce the defined roles of oxidative stress in pluripotent stem cells (PSCs) and hematopoietic stem cells (HSCs) and discuss the potential applications of pharmacological approaches for regulating oxidative stress in regenerative medicine.
American Psychological Association (APA)
Lee, Jungwoon& Cho, Yee Sook& Jung, Haiyoung& Choi, Inpyo. 2018. Pharmacological Regulation of Oxidative Stress in Stem Cells. Oxidative Medicine and Cellular Longevity،Vol. 2018, no. 2018, pp.1-13.
https://search.emarefa.net/detail/BIM-1211382
Modern Language Association (MLA)
Lee, Jungwoon…[et al.]. Pharmacological Regulation of Oxidative Stress in Stem Cells. Oxidative Medicine and Cellular Longevity No. 2018 (2018), pp.1-13.
https://search.emarefa.net/detail/BIM-1211382
American Medical Association (AMA)
Lee, Jungwoon& Cho, Yee Sook& Jung, Haiyoung& Choi, Inpyo. Pharmacological Regulation of Oxidative Stress in Stem Cells. Oxidative Medicine and Cellular Longevity. 2018. Vol. 2018, no. 2018, pp.1-13.
https://search.emarefa.net/detail/BIM-1211382
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1211382