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Oxidative Stress in Poultry: Lessons from the Viral Infections
Joint Authors
Sun, Yingjie
Ding, Chan
Rehman, Zaib Ur
Meng, Chunchun
Safdar, Anum
Pasha, Riaz Hussain
Munir, Muhammad
Source
Oxidative Medicine and Cellular Longevity
Issue
Vol. 2018, Issue 2018 (31 Dec. 2018), pp.1-14, 14 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2018-12-10
Country of Publication
Egypt
No. of Pages
14
Main Subjects
Abstract EN
Reactive species (RS), generally known as reactive oxygen species (ROS) and reactive nitrogen species (RNS), are produced during regular metabolism in the host and are required for many cellular processes such as cytokine transcription, immunomodulation, ion transport, and apoptosis.
Intriguingly, both RNS and ROS are commonly triggered by the pathogenic viruses and are famous for their dual roles in the clearance of viruses and pathological implications.
Uncontrolled production of reactive species results in oxidative stress and causes damage in proteins, lipids, DNA, and cellular structures.
In this review, we describe the production of RS, their detoxification by a cellular antioxidant system, and how these RS damage the proteins, lipids, and DNA.
Given the widespread importance of RS in avian viral diseases, oxidative stress pathways are of utmost importance for targeted therapeutics.
Therefore, a special focus is provided on avian virus-mediated oxidative stresses.
Finally, future research perspectives are discussed on the exploitation of these pathways to treat viral diseases of poultry.
American Psychological Association (APA)
Rehman, Zaib Ur& Meng, Chunchun& Sun, Yingjie& Safdar, Anum& Pasha, Riaz Hussain& Munir, Muhammad…[et al.]. 2018. Oxidative Stress in Poultry: Lessons from the Viral Infections. Oxidative Medicine and Cellular Longevity،Vol. 2018, no. 2018, pp.1-14.
https://search.emarefa.net/detail/BIM-1211573
Modern Language Association (MLA)
Rehman, Zaib Ur…[et al.]. Oxidative Stress in Poultry: Lessons from the Viral Infections. Oxidative Medicine and Cellular Longevity No. 2018 (2018), pp.1-14.
https://search.emarefa.net/detail/BIM-1211573
American Medical Association (AMA)
Rehman, Zaib Ur& Meng, Chunchun& Sun, Yingjie& Safdar, Anum& Pasha, Riaz Hussain& Munir, Muhammad…[et al.]. Oxidative Stress in Poultry: Lessons from the Viral Infections. Oxidative Medicine and Cellular Longevity. 2018. Vol. 2018, no. 2018, pp.1-14.
https://search.emarefa.net/detail/BIM-1211573
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1211573