Alcoholic Beverage and Meal Choices for the Prevention of Noncommunicable Diseases: A Randomized Nutrigenomic Trial
Joint Authors
Di Renzo, Laura
Gratteri, Santo
Sinibaldi Salimei, Paola
Cioccoloni, G.
Ceravolo, Ida
De Lorenzo, Antonino
Source
Oxidative Medicine and Cellular Longevity
Issue
Vol. 2018, Issue 2018 (31 Dec. 2018), pp.1-13, 13 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2018-06-27
Country of Publication
Egypt
No. of Pages
13
Main Subjects
Abstract EN
Background.
Noncommunicable diseases (NCDs) are the first cause of death worldwide.
Mediterranean diet may play a crucial role in the prevention of NCDs, and the presence of wine in this diet could play a positive role on health.
Methods.
54 healthy volunteers consumed one of the following beverages: red (RW) or white wine (WW), vodka (VDK), and/or Mediterranean meal (MeDM) and high-fat meal (HFM).
Results.
OxLDL-C changed significantly between baseline versus HFM, MeDM versus HFM, and HFM versus HFM + RW (p<0.05).
Significant upregulation of catalase (CAT) was observed only after RW.
Conversely, WW, VDK, RW + MeDM, HF + WW, and HF + VDK determined a significant downregulation of CAT gene.
Superoxide dismutase 2 (SOD2) gene expression was upregulated in WW, MeDM + VDK, and RW.
Contrariwise, HFM + VDK determined a downregulation of its expression.
RW, RW + MeDM, and RW + HFM caused the upregulation of glutathione peroxidase-1 (GPX1).
Conclusions.
Our results suggest that the association of low/moderate intake of alcohol beverages, with nutraceutical-proven effectiveness, and ethanol, in association with a Mediterranean diet, could determine a reduction of atherosclerosis risk onset through a positive modulation of antioxidant gene expression helping in the prevention of inflammatory and oxidative damages.
American Psychological Association (APA)
Di Renzo, Laura& Cioccoloni, G.& Sinibaldi Salimei, Paola& Ceravolo, Ida& De Lorenzo, Antonino& Gratteri, Santo. 2018. Alcoholic Beverage and Meal Choices for the Prevention of Noncommunicable Diseases: A Randomized Nutrigenomic Trial. Oxidative Medicine and Cellular Longevity،Vol. 2018, no. 2018, pp.1-13.
https://search.emarefa.net/detail/BIM-1211634
Modern Language Association (MLA)
Di Renzo, Laura…[et al.]. Alcoholic Beverage and Meal Choices for the Prevention of Noncommunicable Diseases: A Randomized Nutrigenomic Trial. Oxidative Medicine and Cellular Longevity No. 2018 (2018), pp.1-13.
https://search.emarefa.net/detail/BIM-1211634
American Medical Association (AMA)
Di Renzo, Laura& Cioccoloni, G.& Sinibaldi Salimei, Paola& Ceravolo, Ida& De Lorenzo, Antonino& Gratteri, Santo. Alcoholic Beverage and Meal Choices for the Prevention of Noncommunicable Diseases: A Randomized Nutrigenomic Trial. Oxidative Medicine and Cellular Longevity. 2018. Vol. 2018, no. 2018, pp.1-13.
https://search.emarefa.net/detail/BIM-1211634
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1211634