Reactive Oxygen Species in Chronic Obstructive Pulmonary Disease
Joint Authors
Boukhenouna, Samia
Wilson, Mark A.
Bahmed, Karim
Kosmider, Beata
Source
Oxidative Medicine and Cellular Longevity
Issue
Vol. 2018, Issue 2018 (31 Dec. 2018), pp.1-9, 9 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2018-02-11
Country of Publication
Egypt
No. of Pages
9
Main Subjects
Abstract EN
Chronic obstructive pulmonary disease (COPD) includes chronic bronchitis and emphysema.
Environmental exposure, primarily cigarette smoking, can cause high oxidative stress and is the main factor of COPD development.
Cigarette smoke also contributes to the imbalance of oxidant/antioxidant due to exogenous reactive oxygen species (ROS).
Moreover, endogenously released ROS during the inflammatory process and mitochondrial dysfunction may contribute to this disease progression.
ROS and reactive nitrogen species (RNS) can oxidize different biomolecules such as DNA, proteins, and lipids leading to epithelial cell injury and death.
Various detoxifying enzymes and antioxidant defense systems can be involved in ROS removal.
In this review, we summarize the main findings regarding the biological role of ROS, which may contribute to COPD development, and cytoprotective mechanisms against this disease progression.
American Psychological Association (APA)
Boukhenouna, Samia& Wilson, Mark A.& Bahmed, Karim& Kosmider, Beata. 2018. Reactive Oxygen Species in Chronic Obstructive Pulmonary Disease. Oxidative Medicine and Cellular Longevity،Vol. 2018, no. 2018, pp.1-9.
https://search.emarefa.net/detail/BIM-1211649
Modern Language Association (MLA)
Boukhenouna, Samia…[et al.]. Reactive Oxygen Species in Chronic Obstructive Pulmonary Disease. Oxidative Medicine and Cellular Longevity No. 2018 (2018), pp.1-9.
https://search.emarefa.net/detail/BIM-1211649
American Medical Association (AMA)
Boukhenouna, Samia& Wilson, Mark A.& Bahmed, Karim& Kosmider, Beata. Reactive Oxygen Species in Chronic Obstructive Pulmonary Disease. Oxidative Medicine and Cellular Longevity. 2018. Vol. 2018, no. 2018, pp.1-9.
https://search.emarefa.net/detail/BIM-1211649
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1211649