Reactive Oxygen Species-Mediated Tumor Microenvironment Transformation: The Mechanism of Radioresistant Gastric Cancer
Joint Authors
Zhou, Fuling
Huang, Tian-he
Wei, Yongchang
Jin, Yanxia
Gu, Huifeng
Shen, Yicheng
Liu, Yin
Sattar, Haseeb
Source
Oxidative Medicine and Cellular Longevity
Issue
Vol. 2018, Issue 2018 (31 Dec. 2018), pp.1-8, 8 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2018-03-27
Country of Publication
Egypt
No. of Pages
8
Main Subjects
Abstract EN
Radioresistance is one of the primary causes responsible for therapeutic failure and recurrence of cancer.
It is well documented that reactive oxygen species (ROS) contribute to the initiation and development of gastric cancer (GC), and the levels of ROS are significantly increased in patients with GC accompanied with abnormal expressions of multiple inflammatory factors.
It is also well documented that ROS can activate cancer cells and inflammatory cells, stimulating the release of a variety of inflammatory cytokines, which subsequently mediates the tumor microenvironment (TME) and promotes cancer stem cell (CSC) maintenance as well as renewal and epithelial-mesenchymal transition (EMT), ultimately resulting in radioresistance and recurrence of GC.
American Psychological Association (APA)
Gu, Huifeng& Huang, Tian-he& Shen, Yicheng& Liu, Yin& Zhou, Fuling& Jin, Yanxia…[et al.]. 2018. Reactive Oxygen Species-Mediated Tumor Microenvironment Transformation: The Mechanism of Radioresistant Gastric Cancer. Oxidative Medicine and Cellular Longevity،Vol. 2018, no. 2018, pp.1-8.
https://search.emarefa.net/detail/BIM-1211681
Modern Language Association (MLA)
Gu, Huifeng…[et al.]. Reactive Oxygen Species-Mediated Tumor Microenvironment Transformation: The Mechanism of Radioresistant Gastric Cancer. Oxidative Medicine and Cellular Longevity No. 2018 (2018), pp.1-8.
https://search.emarefa.net/detail/BIM-1211681
American Medical Association (AMA)
Gu, Huifeng& Huang, Tian-he& Shen, Yicheng& Liu, Yin& Zhou, Fuling& Jin, Yanxia…[et al.]. Reactive Oxygen Species-Mediated Tumor Microenvironment Transformation: The Mechanism of Radioresistant Gastric Cancer. Oxidative Medicine and Cellular Longevity. 2018. Vol. 2018, no. 2018, pp.1-8.
https://search.emarefa.net/detail/BIM-1211681
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1211681