Antiskin Inflammatory Activity of Black Ginger (Kaempferia parviflora) through Antioxidative Activity
Joint Authors
Jang, Mi
Lim, Tae-Gyu
Lee, Myung-hee
Han, Ah-Ram
Choi, Hyo-Kyoung
Lee, Sung-Young
Kim, Kyung-Tack
Source
Oxidative Medicine and Cellular Longevity
Issue
Vol. 2018, Issue 2018 (31 Dec. 2018), pp.1-10, 10 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2018-04-03
Country of Publication
Egypt
No. of Pages
10
Main Subjects
Abstract EN
Kaempferia parviflora (Krachaidum (KD)) is a traditional herbal medicine and has properties that are beneficial for human health.
In the current study, we sought to investigate the anti-inflammatory properties of KD extract (KPE).
In mouse skin tissue, UV light representing solar wavelengths (sUV) increased COX-2 expression, while treatment with KPE reduced this effect.
The anti-inflammatory activity of KPE was confirmed in in vitro models.
MAPK signaling pathways were activated by sUV irradiation, and this was also repressed in the presence of KPE treatment.
It is assumed that the anti-inflammatory activity of KPE is caused by the antioxidative effect.
Furthermore, we confirmed the critical role of oxidative stress in sUV-induced COX-2 expression.
We analyzed the polyphenol composition of KPE.
Of the polyphenols identified, gallic acid, apigenin, and tangeretin were identified as the major polyphenols (at 9.31 ± 1.27, 2.37 ± 0.14, and 2.15 ± 0.19 μg/mg dry weight, resp.).
Collectively, these findings show that in the presence of sUV irradiation, KD has anti-inflammatory properties and antioxidative effects in the skin.
American Psychological Association (APA)
Lee, Myung-hee& Han, Ah-Ram& Jang, Mi& Choi, Hyo-Kyoung& Lee, Sung-Young& Kim, Kyung-Tack…[et al.]. 2018. Antiskin Inflammatory Activity of Black Ginger (Kaempferia parviflora) through Antioxidative Activity. Oxidative Medicine and Cellular Longevity،Vol. 2018, no. 2018, pp.1-10.
https://search.emarefa.net/detail/BIM-1211700
Modern Language Association (MLA)
Lee, Myung-hee…[et al.]. Antiskin Inflammatory Activity of Black Ginger (Kaempferia parviflora) through Antioxidative Activity. Oxidative Medicine and Cellular Longevity No. 2018 (2018), pp.1-10.
https://search.emarefa.net/detail/BIM-1211700
American Medical Association (AMA)
Lee, Myung-hee& Han, Ah-Ram& Jang, Mi& Choi, Hyo-Kyoung& Lee, Sung-Young& Kim, Kyung-Tack…[et al.]. Antiskin Inflammatory Activity of Black Ginger (Kaempferia parviflora) through Antioxidative Activity. Oxidative Medicine and Cellular Longevity. 2018. Vol. 2018, no. 2018, pp.1-10.
https://search.emarefa.net/detail/BIM-1211700
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1211700