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Polyphenolic Compounds, Antioxidant, and Cardioprotective Effects of Pomace Extracts from Fetească Neagră Cultivar
Joint Authors
Pârvu, Alina E.
Pârvu, Marcel
Balea, Ştefania Silvia
Pop, Nastasia
Marín, Fernando Zamora
Source
Oxidative Medicine and Cellular Longevity
Issue
Vol. 2018, Issue 2018 (31 Dec. 2018), pp.1-11, 11 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2018-03-22
Country of Publication
Egypt
No. of Pages
11
Main Subjects
Abstract EN
Grape pomace is a potential source of natural antioxidant agents.
Phenolic compounds and antioxidant and cardioprotective properties of fresh and fermented pomace extracts obtained from Vitis vinifera L.
red variety Fetească neagră grown in Romania in 2015 were investigated.
Grape pomace extracts total phenolic index, total tannins, total anthocyanins, proanthocyanidins, flavan-3-ol monomers, stilbenes, and DPPH free radical scavenger were measured.
The effect of a seven-day pretreatment with grape pomace extracts on the isoprenaline-induced infarct-like lesion in rats was assessed by ECG monitoring, serum levels of creatine kinase, aspartate transaminase, and alanine transaminase.
Total serum oxidative status, total antioxidant response, oxidative stress index, malondialdehyde, total thiols, and nitric oxide have been also assessed.
Higher phenolic content and antioxidant activity were found in fermented pomace extracts when compared to fresh pomace extracts.
Pretreatment with grape pomace extracts significantly improved cardiac and oxidative stress parameters.
In conclusion, Fetească neagră pomace extracts had a good in vitro antioxidant activity due to an important phenolic content.
In vivo, the extracts had cardioprotective effects against isoprenaline-induced infarct-like lesion by reducing oxidative stress, fresh pomace extracts having a better effect.
American Psychological Association (APA)
Balea, Ştefania Silvia& Pârvu, Alina E.& Pop, Nastasia& Marín, Fernando Zamora& Pârvu, Marcel. 2018. Polyphenolic Compounds, Antioxidant, and Cardioprotective Effects of Pomace Extracts from Fetească Neagră Cultivar. Oxidative Medicine and Cellular Longevity،Vol. 2018, no. 2018, pp.1-11.
https://search.emarefa.net/detail/BIM-1212161
Modern Language Association (MLA)
Balea, Ştefania Silvia…[et al.]. Polyphenolic Compounds, Antioxidant, and Cardioprotective Effects of Pomace Extracts from Fetească Neagră Cultivar. Oxidative Medicine and Cellular Longevity No. 2018 (2018), pp.1-11.
https://search.emarefa.net/detail/BIM-1212161
American Medical Association (AMA)
Balea, Ştefania Silvia& Pârvu, Alina E.& Pop, Nastasia& Marín, Fernando Zamora& Pârvu, Marcel. Polyphenolic Compounds, Antioxidant, and Cardioprotective Effects of Pomace Extracts from Fetească Neagră Cultivar. Oxidative Medicine and Cellular Longevity. 2018. Vol. 2018, no. 2018, pp.1-11.
https://search.emarefa.net/detail/BIM-1212161
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1212161