In Vivo Evaluation of the Antioxidant Activity and Protective Action of the Seaweed Gracilaria birdiae
Joint Authors
Gomes, Dayanne Lopes
Barros-Gomes, Joanna Angelis Costa
Nascimento, Daiany Laise Araújo
Silveira, Ana Cristina Rodrigues
Silva, Rayanne Kelly
Melo, Karoline Rachel Teodosio
Almeida-Lima, Jailma
Camara, Rafael Barros Gomes
Silva, Naisandra Bezerra da
Rocha, Hugo Alexandre Oliveira
Source
Oxidative Medicine and Cellular Longevity
Issue
Vol. 2018, Issue 2018 (31 Dec. 2018), pp.1-12, 12 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2018-08-01
Country of Publication
Egypt
No. of Pages
12
Main Subjects
Abstract EN
The red seaweed Gracilaria birdiae (GB) is farmed and used as food in northeast Brazil.
However, the economic potential of this seaweed has been explored little.
To enable direct consumption and/or product diversification from GB, it is necessary to evaluate its effect in vivo.
In this study, the food of mice was improved with the addition of GB.
After 21 days, the consumption of seaweed reduced the weight gain and blood glucose levels in mice.
In addition, it increased the trolox equivalent antioxidant capacity and glutathione reductase and catalase levels compared to those of the control group.
In addition, some mice also received carbon tetrachloride (CCl4).
In this case, histological, enzymatic, and antioxidant tests showed that the seaweed could protect animals from damage caused by this toxic agent.
In addition, GB aqueous extract (AE) inhibited 50% of 3T3-L1 cell differentiation into adipocytes, whereas GB ethanolic extract was not effective.
AE is composed mainly of sulfated polysaccharides.
The results of the present study indicate that the alga GB protected the mice from CCl4-induced damage, indicating that the seaweed exhibits protective action in vivo.
In addition, GB decreased the animal weight gain, which was mainly due to the action of the sulfated polysaccharides synthesized by this seaweed.
American Psychological Association (APA)
Barros-Gomes, Joanna Angelis Costa& Nascimento, Daiany Laise Araújo& Silveira, Ana Cristina Rodrigues& Silva, Rayanne Kelly& Gomes, Dayanne Lopes& Melo, Karoline Rachel Teodosio…[et al.]. 2018. In Vivo Evaluation of the Antioxidant Activity and Protective Action of the Seaweed Gracilaria birdiae. Oxidative Medicine and Cellular Longevity،Vol. 2018, no. 2018, pp.1-12.
https://search.emarefa.net/detail/BIM-1212372
Modern Language Association (MLA)
Barros-Gomes, Joanna Angelis Costa…[et al.]. In Vivo Evaluation of the Antioxidant Activity and Protective Action of the Seaweed Gracilaria birdiae. Oxidative Medicine and Cellular Longevity No. 2018 (2018), pp.1-12.
https://search.emarefa.net/detail/BIM-1212372
American Medical Association (AMA)
Barros-Gomes, Joanna Angelis Costa& Nascimento, Daiany Laise Araújo& Silveira, Ana Cristina Rodrigues& Silva, Rayanne Kelly& Gomes, Dayanne Lopes& Melo, Karoline Rachel Teodosio…[et al.]. In Vivo Evaluation of the Antioxidant Activity and Protective Action of the Seaweed Gracilaria birdiae. Oxidative Medicine and Cellular Longevity. 2018. Vol. 2018, no. 2018, pp.1-12.
https://search.emarefa.net/detail/BIM-1212372
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1212372