Association of Ischemic Cardiovascular Disease with Inadequacy of Liver Store of Retinol in Elderly Individuals
Joint Authors
Ramalho, A.
Lima, I. O. L.
Peres, W. A. F.
Cruz, S.
Source
Oxidative Medicine and Cellular Longevity
Issue
Vol. 2018, Issue 2018 (31 Dec. 2018), pp.1-6, 6 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2018-04-02
Country of Publication
Egypt
No. of Pages
6
Main Subjects
Abstract EN
Objective.
Vitamin A antioxidant role has an important relationship with the metabolic processes of aging and cardiovascular disease (CVD).
This study aimed at assessing the liver store of retinol in elderly individuals who died from cardiovascular disease and its relationship with liver weight and body weight.
Methods and Results.
This is a cross-sectional study conducted in necropsied individuals, aged 60 years or over, until 48 hours postmortem.
The study assessed 65 elderly individuals who died from ischemic heart diseases (G1), cerebrovascular diseases (G2), other forms of heart disease (G3), or infectious heart diseases (G4).
Twenty percent had inadequate liver store of retinol.
G1 showed lower median of liver store of retinol when compared to G3 (p<0.001), and G3 showed the highest median when compared to G2 (p=0.007).
A significant association was observed between inadequate liver store of retinol and death by ischemic CVD (G1) (p=0.001) with an odds ratio of 10.38.
It was observed that individuals with higher body weight and liver weight showed lower liver store of retinol with significant differences (p=0.027 and p=0.026).
Conclusion.
Ischemic CVD and increased body weight and liver weight are related to a greater impairment of the liver store of retinol.
American Psychological Association (APA)
Lima, I. O. L.& Peres, W. A. F.& Cruz, S.& Ramalho, A.. 2018. Association of Ischemic Cardiovascular Disease with Inadequacy of Liver Store of Retinol in Elderly Individuals. Oxidative Medicine and Cellular Longevity،Vol. 2018, no. 2018, pp.1-6.
https://search.emarefa.net/detail/BIM-1212407
Modern Language Association (MLA)
Lima, I. O. L.…[et al.]. Association of Ischemic Cardiovascular Disease with Inadequacy of Liver Store of Retinol in Elderly Individuals. Oxidative Medicine and Cellular Longevity No. 2018 (2018), pp.1-6.
https://search.emarefa.net/detail/BIM-1212407
American Medical Association (AMA)
Lima, I. O. L.& Peres, W. A. F.& Cruz, S.& Ramalho, A.. Association of Ischemic Cardiovascular Disease with Inadequacy of Liver Store of Retinol in Elderly Individuals. Oxidative Medicine and Cellular Longevity. 2018. Vol. 2018, no. 2018, pp.1-6.
https://search.emarefa.net/detail/BIM-1212407
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1212407