Absent Audiovisual Integration Elicited by Peripheral Stimuli in Parkinson’s Disease
Joint Authors
Ren, Yanna
Yang, Weiping
Ren, Yanling
Wu, Fengxia
Yang, Jiajia
Takahashi, Satoshi
Ejima, Yoshimichi
Wu, Jinglong
Hirata, Koichi
Suzuki, Keisuke
Source
Issue
Vol. 2018, Issue 2018 (31 Dec. 2018), pp.1-10, 10 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2018-04-12
Country of Publication
Egypt
No. of Pages
10
Main Subjects
Abstract EN
The basal ganglia, which have been shown to be a significant multisensory hub, are disordered in Parkinson’s disease (PD).
This study was to investigate the audiovisual integration of peripheral stimuli in PD patients with/without sleep disturbances.
Thirty-six age-matched normal controls (NC) and 30 PD patients were recruited for an auditory/visual discrimination experiment.
The mean response times for each participant were analyzed using repeated measures ANOVA and race model.
The results showed that the response to all stimuli was significantly delayed for PD compared to NC (all p<0.01).
The response to audiovisual stimuli was significantly faster than that to unimodal stimuli in both NC and PD (p<0.001).
Additionally, audiovisual integration was absent in PD; however, it did occur in NC.
Further analysis showed that there was no significant audiovisual integration in PD with/without cognitive impairment or in PD with/without sleep disturbances.
Furthermore, audiovisual facilitation was not associated with Hoehn and Yahr stage, disease duration, or the presence of sleep disturbances (all p>0.05).
The current results showed that audiovisual multisensory integration for peripheral stimuli is absent in PD regardless of sleep disturbances and further suggested the abnormal audiovisual integration might be a potential early manifestation of PD.
American Psychological Association (APA)
Ren, Yanna& Suzuki, Keisuke& Yang, Weiping& Ren, Yanling& Wu, Fengxia& Yang, Jiajia…[et al.]. 2018. Absent Audiovisual Integration Elicited by Peripheral Stimuli in Parkinson’s Disease. Parkinson’s Disease،Vol. 2018, no. 2018, pp.1-10.
https://search.emarefa.net/detail/BIM-1212447
Modern Language Association (MLA)
Ren, Yanna…[et al.]. Absent Audiovisual Integration Elicited by Peripheral Stimuli in Parkinson’s Disease. Parkinson’s Disease No. 2018 (2018), pp.1-10.
https://search.emarefa.net/detail/BIM-1212447
American Medical Association (AMA)
Ren, Yanna& Suzuki, Keisuke& Yang, Weiping& Ren, Yanling& Wu, Fengxia& Yang, Jiajia…[et al.]. Absent Audiovisual Integration Elicited by Peripheral Stimuli in Parkinson’s Disease. Parkinson’s Disease. 2018. Vol. 2018, no. 2018, pp.1-10.
https://search.emarefa.net/detail/BIM-1212447
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1212447