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Magnesium Sulfate as Adjuvant in Prehospital Femoral Nerve Block for a Patient with Diaphysial Femoral Fracture: A Randomized Controlled Trial
Joint Authors
Kahloul, Mohamed
Naija, Walid
Jebali, Chawki
Hassine, Nesrine Ibn
Jaouadi, Mohamed Aymen
Ferhi, Fehmi
Chebili, Naoufel
Source
Issue
Vol. 2018, Issue 2018 (31 Dec. 2018), pp.1-5, 5 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2018-12-03
Country of Publication
Egypt
No. of Pages
5
Main Subjects
Abstract EN
Introduction.
Prehospital management of traumatic pain is commonly based on morphine while locoregional analgesia techniques, especially the femoral nerve block (FNB), can be safely and efficiently used.
Adjuvants uses can reduce local anesthetic doses and decrease their related risk.
The aim of the study was to assess the analgesic effect of magnesium sulfate when used as an adjuvant in prehospital FNB.
Methods.
This is a randomized double-blinded trial conducted in a prehospital medical department of an academic hospital.
Patients with isolated diaphysial femoral fracture and eligible to participate were randomized into 2 groups.
Group C had a FNB with 15 ml of lidocaine with epinephrine (300 mg) and 3 ml of normal saline solution.
Group I had a FNB with 15 ml of lidocaine with epinephrine (300 mg) and 3 ml of MgS 15% (450 mg).
The FNB was performed according to the WINNIE technique.
Primary endpoints were morphine consumption and pain intensity during the first 6 hours.
Secondary endpoints were the duration of the sensory block, time to the first analgesic request, and side effects occurrence.
Results.
Twenty-four patients were enrolled in each group.
Both groups were comparable according to demographic characteristics, initial pain scores, and vital constants.
In group I, morphine requirements were significantly lower (2 ± 2 mg versus 5 ± 3 mg, p<10−3), analgesic onset was significantly faster, and the average time to the first analgesic request was longer (276 ± 139 min versus 160 ± 79 min, p<10−3).
The average duration of sensory block was longer in group I (226 ± 64 min versus 116 ± 70 min p<10−3).
No side effects were recorded.
Conclusion.
Magnesium sulfate should be considered as an efficient and safe adjuvant to lidocaine in prehospital FNB.
This trial is registered with (NCT03597945).
American Psychological Association (APA)
Jebali, Chawki& Kahloul, Mohamed& Hassine, Nesrine Ibn& Jaouadi, Mohamed Aymen& Ferhi, Fehmi& Naija, Walid…[et al.]. 2018. Magnesium Sulfate as Adjuvant in Prehospital Femoral Nerve Block for a Patient with Diaphysial Femoral Fracture: A Randomized Controlled Trial. Pain Research and Management،Vol. 2018, no. 2018, pp.1-5.
https://search.emarefa.net/detail/BIM-1212548
Modern Language Association (MLA)
Jebali, Chawki…[et al.]. Magnesium Sulfate as Adjuvant in Prehospital Femoral Nerve Block for a Patient with Diaphysial Femoral Fracture: A Randomized Controlled Trial. Pain Research and Management No. 2018 (2018), pp.1-5.
https://search.emarefa.net/detail/BIM-1212548
American Medical Association (AMA)
Jebali, Chawki& Kahloul, Mohamed& Hassine, Nesrine Ibn& Jaouadi, Mohamed Aymen& Ferhi, Fehmi& Naija, Walid…[et al.]. Magnesium Sulfate as Adjuvant in Prehospital Femoral Nerve Block for a Patient with Diaphysial Femoral Fracture: A Randomized Controlled Trial. Pain Research and Management. 2018. Vol. 2018, no. 2018, pp.1-5.
https://search.emarefa.net/detail/BIM-1212548
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1212548