Local Anesthetic Wound Infiltration after Osteosynthesis of Extracapsular Hip Fracture Does Not Reduce Pain or Opioid Requirements: A Randomized, Placebo-Controlled, Double-Blind Clinical Trial in 49 Patients
Joint Authors
Overgaard, Søren
Bech, R. D.
Lauritsen, Jens
Ovesen, Ole
Emmeluth, Claus
Lindholm, Peter
Source
Issue
Vol. 2018, Issue 2018 (31 Dec. 2018), pp.1-7, 7 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2018-11-13
Country of Publication
Egypt
No. of Pages
7
Main Subjects
Abstract EN
Background and purpose.
Local infiltration analgesia (LIA) supports early mobilization after hip and knee arthroplasty.
Inspired by this, we studied the effectiveness of wound infiltration with the long acting local anesthetic ropivacaine in an effort to decrease the need for postoperative opioids after osteosynthesis of extracapsular hip fracture.
Methods.
Forty-nine patients undergoing osteosynthesis with a sliding hip screw were randomized into two groups in a double-blind study (ClinicalTrials.gov:NCT01119209).
The patients received intraoperative infiltration followed by 6 postoperative injections through a wound catheter in eight-hour intervals.
23 patients received ropivacaine and 26 received saline.
The intervention period was 2 days, and the observation period was 5 days.
In both groups, there were no restrictions on the total daily dose of opioids.
Pain was assessed at specific postoperative time points, and the daily opioid usage was registered.
Results.
Intraoperative infiltration with 200 mg ropivacaine and postoperative repeated infiltration with 100 mg ropivacaine did not result in statistically significant difference between the groups regarding postoperative opioid consumption or pain.
Interpretation.
Ropivacaine as single component in postoperative treatment of pain after hip fracture is not effective.
In our setup, wound infiltration with ropivacaine is not statistically significantly better than placebo.
American Psychological Association (APA)
Bech, R. D.& Ovesen, Ole& Lauritsen, Jens& Emmeluth, Claus& Lindholm, Peter& Overgaard, Søren. 2018. Local Anesthetic Wound Infiltration after Osteosynthesis of Extracapsular Hip Fracture Does Not Reduce Pain or Opioid Requirements: A Randomized, Placebo-Controlled, Double-Blind Clinical Trial in 49 Patients. Pain Research and Management،Vol. 2018, no. 2018, pp.1-7.
https://search.emarefa.net/detail/BIM-1212592
Modern Language Association (MLA)
Bech, R. D.…[et al.]. Local Anesthetic Wound Infiltration after Osteosynthesis of Extracapsular Hip Fracture Does Not Reduce Pain or Opioid Requirements: A Randomized, Placebo-Controlled, Double-Blind Clinical Trial in 49 Patients. Pain Research and Management No. 2018 (2018), pp.1-7.
https://search.emarefa.net/detail/BIM-1212592
American Medical Association (AMA)
Bech, R. D.& Ovesen, Ole& Lauritsen, Jens& Emmeluth, Claus& Lindholm, Peter& Overgaard, Søren. Local Anesthetic Wound Infiltration after Osteosynthesis of Extracapsular Hip Fracture Does Not Reduce Pain or Opioid Requirements: A Randomized, Placebo-Controlled, Double-Blind Clinical Trial in 49 Patients. Pain Research and Management. 2018. Vol. 2018, no. 2018, pp.1-7.
https://search.emarefa.net/detail/BIM-1212592
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1212592