Perioperative Immunosuppression and Risk of Cancer Progression: The Impact of Opioids on Pain Management
Joint Authors
Mika, Joanna
Leppert, Wojciech
Zajączkowska, Renata
Kocot-Kępska, Magdalena
Woroń, Jarosław
Wrzosek, Anna
Wordliczek, Jerzy
Source
Issue
Vol. 2018, Issue 2018 (31 Dec. 2018), pp.1-8, 8 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2018-09-19
Country of Publication
Egypt
No. of Pages
8
Main Subjects
Abstract EN
Opioids comprise an important group of drugs used in cancer pain pharmacotherapy.
In recent years, more and more studies have emerged indicating the potentially immunosuppressive effects of opioid analgesics and their serious consequences, including the risk of cancer progression.
The identification of these risks has prompted a search for other effective, and most importantly, safer methods of perioperative analgesic management.
Regional analgesia techniques, which allow for a significant reduction in opioid dosing and thus diminish the risk of immunosuppression associated with these drugs, seem to offer substantial hope in this respect.
A number of studies available in the literature assess the effects of regional analgesia techniques on cancer progression; however, it is often difficult to interpret their results owing to several perioperative factors (such as surgical trauma, inadequate pain and stress relief, and hypothermia) which are also attributed immunosuppressive effects and tend to be implicated in increased risk of cancer progression.
Further research is needed to verify the available data on both the potential adverse effects of opioids and the possible protective effects of regional analgesia techniques on cancer patients.
American Psychological Association (APA)
Zajączkowska, Renata& Leppert, Wojciech& Mika, Joanna& Kocot-Kępska, Magdalena& Woroń, Jarosław& Wrzosek, Anna…[et al.]. 2018. Perioperative Immunosuppression and Risk of Cancer Progression: The Impact of Opioids on Pain Management. Pain Research and Management،Vol. 2018, no. 2018, pp.1-8.
https://search.emarefa.net/detail/BIM-1212625
Modern Language Association (MLA)
Zajączkowska, Renata…[et al.]. Perioperative Immunosuppression and Risk of Cancer Progression: The Impact of Opioids on Pain Management. Pain Research and Management No. 2018 (2018), pp.1-8.
https://search.emarefa.net/detail/BIM-1212625
American Medical Association (AMA)
Zajączkowska, Renata& Leppert, Wojciech& Mika, Joanna& Kocot-Kępska, Magdalena& Woroń, Jarosław& Wrzosek, Anna…[et al.]. Perioperative Immunosuppression and Risk of Cancer Progression: The Impact of Opioids on Pain Management. Pain Research and Management. 2018. Vol. 2018, no. 2018, pp.1-8.
https://search.emarefa.net/detail/BIM-1212625
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1212625