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Epidemiology of Adult Soft-Tissue Sarcomas in Germany
Joint Authors
Kaye, James A.
Saltus, Catherine W.
Calingaert, Brian
D’yachkova, Yulia
Candrilli, Sean D.
Lorenzo, Maria
Otto, Thorsten
Wagner, Uwe
Source
Issue
Vol. 2018, Issue 2018 (31 Dec. 2018), pp.1-11, 11 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2018-04-04
Country of Publication
Egypt
No. of Pages
11
Main Subjects
Abstract EN
We conducted a retrospective cohort study using data compiled from the regional German cancer registries by the Centre for Cancer Registry Data (ZfKD) at the Robert Koch Institut (RKI) to describe the epidemiology of adult soft-tissue sarcomas (STS) in Germany in 2003–2012, focusing on advanced STS.
We identified 33,803 incident adult cases of STS (other than the Kaposi sarcoma and gastrointestinal stromal tumors).
The incidence of STS was 6.05 (95% confidence interval (CI), 5.82–6.29) per 100,000 in 2012 (4,079 cases).
During 2003–2012, the most common histologic categories were leiomyosarcoma (19%), liposarcoma (16%), and STS not otherwise specified (14%).
The overall STS-specific mortality rate in 2012 was 2.31 (95% CI, 2.06–2.57) per 100,000, and the median overall survival from initial diagnosis was 5.83 (95% CI, 5.50–6.08) years.
Using STS mortality rates as a proxy for incidence of advanced STS in Germany and applying the age- and sex-specific rates to the corresponding German population, we estimated that 1,581 incident adult advanced STS cases occurred in Germany in 2012.
Our findings contribute to a refined understanding of the population burden of STS in Germany, including the number of patients with advanced STS who may be candidates for systemic treatment.
American Psychological Association (APA)
Saltus, Catherine W.& Calingaert, Brian& Candrilli, Sean D.& Lorenzo, Maria& D’yachkova, Yulia& Otto, Thorsten…[et al.]. 2018. Epidemiology of Adult Soft-Tissue Sarcomas in Germany. Complexity،Vol. 2018, no. 2018, pp.1-11.
https://search.emarefa.net/detail/BIM-1212825
Modern Language Association (MLA)
Saltus, Catherine W.…[et al.]. Epidemiology of Adult Soft-Tissue Sarcomas in Germany. Complexity No. 2018 (2018), pp.1-11.
https://search.emarefa.net/detail/BIM-1212825
American Medical Association (AMA)
Saltus, Catherine W.& Calingaert, Brian& Candrilli, Sean D.& Lorenzo, Maria& D’yachkova, Yulia& Otto, Thorsten…[et al.]. Epidemiology of Adult Soft-Tissue Sarcomas in Germany. Complexity. 2018. Vol. 2018, no. 2018, pp.1-11.
https://search.emarefa.net/detail/BIM-1212825
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1212825