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Addressing the Adult Soft Tissue Sarcoma Microenvironment with Intratumoral Immunotherapy
Joint Authors
Raj, Shailaja
Miller, Lance D.
Triozzi, Pierre L.
Source
Issue
Vol. 2018, Issue 2018 (31 Dec. 2018), pp.1-10, 10 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2018-08-12
Country of Publication
Egypt
No. of Pages
10
Main Subjects
Abstract EN
Sarcoma is comprised of a heterogeneous group of tumors originating from the mesenchyme.
Sarcoma is also the first tumor that responded to immunotherapeutic agents often termed as “Coley’s toxins.” However, immunotherapy is yet to establish its presence in sarcomas.
Complex interactions between tumor and immune cells in the tumor microenvironment play a crucial role in response to immunotherapy.
There is a dynamic equilibrium created by the immune cells infiltrating the tumor, and this forms the basis of tumor evasion.
Manipulating the intratumoral microenvironment will help overcome tumor evasion.
American Psychological Association (APA)
Raj, Shailaja& Miller, Lance D.& Triozzi, Pierre L.. 2018. Addressing the Adult Soft Tissue Sarcoma Microenvironment with Intratumoral Immunotherapy. Complexity،Vol. 2018, no. 2018, pp.1-10.
https://search.emarefa.net/detail/BIM-1212845
Modern Language Association (MLA)
Raj, Shailaja…[et al.]. Addressing the Adult Soft Tissue Sarcoma Microenvironment with Intratumoral Immunotherapy. Complexity No. 2018 (2018), pp.1-10.
https://search.emarefa.net/detail/BIM-1212845
American Medical Association (AMA)
Raj, Shailaja& Miller, Lance D.& Triozzi, Pierre L.. Addressing the Adult Soft Tissue Sarcoma Microenvironment with Intratumoral Immunotherapy. Complexity. 2018. Vol. 2018, no. 2018, pp.1-10.
https://search.emarefa.net/detail/BIM-1212845
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1212845