Effectiveness of Integrated Neurocognitive Therapy on Cognitive Impairment and Functional Outcome for Schizophrenia Outpatients
Joint Authors
Galeoto, Giovanni
De Mare, Andreana
Cantarella, Miriam
Source
Schizophrenia Research and Treatment
Issue
Vol. 2018, Issue 2018 (31 Dec. 2018), pp.1-9, 9 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2018-10-21
Country of Publication
Egypt
No. of Pages
9
Main Subjects
Abstract EN
Cognitive impairment is highly prevalent in patients with schizophrenia and schizoaffective disorder.
Many interventions have been developed to treat cognitive deficit, since it has a strong impact on functional outcome; however, there are no integrated interventions targeting multiple neuro- and social-cognitive domains with a particular focus on the generalization of the effects of therapy on the functional outcome.
Recently, a group of experts has developed a cognitive remediation group therapy approach called Integrated Neurocognitive Therapy (INT), which includes exercises to improve the MATRICS (Measurement and Treatment Research to Improve Cognition in Schizophrenia) neuro- and social-cognitive domains.
This systematic review and meta-analysis aimed to assess the efficacy of this approach.
We conducted a search of PubMed, Scopus, Web of Science, and PsycINFO to select primary studies evaluating INT in schizophrenic and schizoaffective patients.
The primary outcomes of the meta-analysis included negative and positive symptoms and global functioning.
Two randomized controlled trials met inclusion criteria.
A total of 217 participants were included.
Based on the results from the Positive and Negative Syndrome Scale (PANSS), a significant pooled effect size was observed for negative symptoms, which demonstrated not only an improvement in the patients treated immediately after therapy but also a permanence of positive results at a 9–12-month follow-up.
On the other hand, no significant effect size was observed for positive symptoms.
In addition, a significant pooled effect size was found for Global Assessment of Functioning (GAF), which shows how INT’s integrated approach has lasting positive implications on patients’ functional outcome.
We concluded that INT might be an effective treatment for negative symptoms and global functioning in patients with schizophrenia, compared to treatment as usual (TAU).
American Psychological Association (APA)
De Mare, Andreana& Cantarella, Miriam& Galeoto, Giovanni. 2018. Effectiveness of Integrated Neurocognitive Therapy on Cognitive Impairment and Functional Outcome for Schizophrenia Outpatients. Schizophrenia Research and Treatment،Vol. 2018, no. 2018, pp.1-9.
https://search.emarefa.net/detail/BIM-1213040
Modern Language Association (MLA)
De Mare, Andreana…[et al.]. Effectiveness of Integrated Neurocognitive Therapy on Cognitive Impairment and Functional Outcome for Schizophrenia Outpatients. Schizophrenia Research and Treatment No. 2018 (2018), pp.1-9.
https://search.emarefa.net/detail/BIM-1213040
American Medical Association (AMA)
De Mare, Andreana& Cantarella, Miriam& Galeoto, Giovanni. Effectiveness of Integrated Neurocognitive Therapy on Cognitive Impairment and Functional Outcome for Schizophrenia Outpatients. Schizophrenia Research and Treatment. 2018. Vol. 2018, no. 2018, pp.1-9.
https://search.emarefa.net/detail/BIM-1213040
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1213040