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An Event Related Potentials Study of Semantic Coherence Effect during Episodic Encoding in Schizophrenia Patients
Joint Authors
Battal Merlet, Lâle
Blanchet, Alain
Lockman, Hazlin
Kostova, Milena
Source
Schizophrenia Research and Treatment
Issue
Vol. 2018, Issue 2018 (31 Dec. 2018), pp.1-15, 15 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2018-01-01
Country of Publication
Egypt
No. of Pages
15
Main Subjects
Abstract EN
The objective of this electrophysiological study was to investigate the processing of semantic coherence during encoding in relation to episodic memory processes promoted at test, in schizophrenia patients, by using the N400 paradigm.
Eighteen schizophrenia patients and 15 healthy participants undertook a recognition memory task.
The stimuli consisted of pairs of words either semantically related or unrelated to a given category name (context).
During encoding, both groups exhibited an N400 external semantic coherence effect.
Healthy controls also showed an N400 internal semantic coherence effect, but this effect was not present in patients.
At test, related stimuli were accompanied by an FN400 old/new effect in both groups and by a parietal old/new effect in the control group alone.
In the patient group, external semantic coherence effect was associated with FN400, while, in the control group, it was correlated to the parietal old/new effect.
Our results indicate that schizophrenia patients can process the contextual information at encoding to enhance familiarity process for related stimuli at test.
Therefore, cognitive rehabilitation therapies targeting the implementation of semantic encoding strategies can mobilize familiarity which in turn can overcome the recollection deficit, promoting successful episodic memory performance in schizophrenia patients.
American Psychological Association (APA)
Battal Merlet, Lâle& Blanchet, Alain& Lockman, Hazlin& Kostova, Milena. 2018. An Event Related Potentials Study of Semantic Coherence Effect during Episodic Encoding in Schizophrenia Patients. Schizophrenia Research and Treatment،Vol. 2018, no. 2018, pp.1-15.
https://search.emarefa.net/detail/BIM-1213056
Modern Language Association (MLA)
Battal Merlet, Lâle…[et al.]. An Event Related Potentials Study of Semantic Coherence Effect during Episodic Encoding in Schizophrenia Patients. Schizophrenia Research and Treatment No. 2018 (2018), pp.1-15.
https://search.emarefa.net/detail/BIM-1213056
American Medical Association (AMA)
Battal Merlet, Lâle& Blanchet, Alain& Lockman, Hazlin& Kostova, Milena. An Event Related Potentials Study of Semantic Coherence Effect during Episodic Encoding in Schizophrenia Patients. Schizophrenia Research and Treatment. 2018. Vol. 2018, no. 2018, pp.1-15.
https://search.emarefa.net/detail/BIM-1213056
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1213056