Deubiquitinating Enzymes and Bone Remodeling
Joint Authors
Guo, Yu-chen
Yuan, Quan
Zhang, Shi-wen
Source
Issue
Vol. 2018, Issue 2018 (31 Dec. 2018), pp.1-9, 9 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2018-07-08
Country of Publication
Egypt
No. of Pages
9
Abstract EN
Bone remodeling, which is essential for bone homeostasis, is controlled by multiple factors and mechanisms.
In the past few years, studies have emphasized the role of the ubiquitin-dependent proteolysis system in regulating bone remodeling.
Deubiquitinases, which are grouped into five families, remove ubiquitin from target proteins and are involved in several cell functions.
Importantly, a number of deubiquitinases mediate bone remodeling through regulating differentiation and/or function of osteoblast and osteoclasts.
In this review, we review the functions and mechanisms of deubiquitinases in mediating bone remodeling.
American Psychological Association (APA)
Guo, Yu-chen& Zhang, Shi-wen& Yuan, Quan. 2018. Deubiquitinating Enzymes and Bone Remodeling. Stem Cells International،Vol. 2018, no. 2018, pp.1-9.
https://search.emarefa.net/detail/BIM-1213363
Modern Language Association (MLA)
Guo, Yu-chen…[et al.]. Deubiquitinating Enzymes and Bone Remodeling. Stem Cells International No. 2018 (2018), pp.1-9.
https://search.emarefa.net/detail/BIM-1213363
American Medical Association (AMA)
Guo, Yu-chen& Zhang, Shi-wen& Yuan, Quan. Deubiquitinating Enzymes and Bone Remodeling. Stem Cells International. 2018. Vol. 2018, no. 2018, pp.1-9.
https://search.emarefa.net/detail/BIM-1213363
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1213363