Cancer Stem Cells (CSCs) in Drug Resistance and their Therapeutic Implications in Cancer Treatment
Joint Authors
Phi, Lan Thi Hanh
Sari, Ita Novita
Yang, Ying-Gui
Lee, Sang-Hyun
Jun, Nayoung
Kim, Kwang Seock
Lee, Yun Kyung
Kwon, Hyog Young
Source
Issue
Vol. 2018, Issue 2018 (31 Dec. 2018), pp.1-16, 16 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2018-02-28
Country of Publication
Egypt
No. of Pages
16
Abstract EN
Cancer stem cells (CSCs), also known as tumor-initiating cells (TICs), are suggested to be responsible for drug resistance and cancer relapse due in part to their ability to self-renew themselves and differentiate into heterogeneous lineages of cancer cells.
Thus, it is important to understand the characteristics and mechanisms by which CSCs display resistance to therapeutic agents.
In this review, we highlight the key features and mechanisms that regulate CSC function in drug resistance as well as recent breakthroughs of therapeutic approaches for targeting CSCs.
This promises new insights of CSCs in drug resistance and provides better therapeutic rationales to accompany novel anticancer therapeutics.
American Psychological Association (APA)
Phi, Lan Thi Hanh& Sari, Ita Novita& Yang, Ying-Gui& Lee, Sang-Hyun& Jun, Nayoung& Kim, Kwang Seock…[et al.]. 2018. Cancer Stem Cells (CSCs) in Drug Resistance and their Therapeutic Implications in Cancer Treatment. Stem Cells International،Vol. 2018, no. 2018, pp.1-16.
https://search.emarefa.net/detail/BIM-1213471
Modern Language Association (MLA)
Phi, Lan Thi Hanh…[et al.]. Cancer Stem Cells (CSCs) in Drug Resistance and their Therapeutic Implications in Cancer Treatment. Stem Cells International No. 2018 (2018), pp.1-16.
https://search.emarefa.net/detail/BIM-1213471
American Medical Association (AMA)
Phi, Lan Thi Hanh& Sari, Ita Novita& Yang, Ying-Gui& Lee, Sang-Hyun& Jun, Nayoung& Kim, Kwang Seock…[et al.]. Cancer Stem Cells (CSCs) in Drug Resistance and their Therapeutic Implications in Cancer Treatment. Stem Cells International. 2018. Vol. 2018, no. 2018, pp.1-16.
https://search.emarefa.net/detail/BIM-1213471
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1213471