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Direct Control of Stem Cell Behavior Using Biomaterials and Genetic Factors
Joint Authors
Lee, Jin Woo
Yoon, Jeong-Kee
Kang, Mi-Lan
Park, Joo Hyun
Lee, Kyoung-Mi
Shin, Young Min
Sung, Hak-Joon
Kim, Hyun Ok
Source
Issue
Vol. 2018, Issue 2018 (31 Dec. 2018), pp.1-17, 17 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2018-05-10
Country of Publication
Egypt
No. of Pages
17
Abstract EN
Stem cells have recently emerged as an important candidate for cell therapy.
However, some major limitations still exist such as a small quantity of cell supply, senescence, and insufficient differentiation efficiency.
Therefore, there is an unmet need to control stem cell behavior for better clinical performance.
Since native microenvironment factors including stem cell niche, genetic factors, and growth factors direct stem cell fate cooperatively, user-specified in vitro settings are required to understand the regulatory roles and effects of each factor, thereby applying the factors for improved cell therapy.
Among others, various types of biomaterials and transfection method have been employed as key tools for development of the in vitro settings.
This review focuses on the current strategies to improve stemness maintenance, direct differentiation, and reprogramming using biomaterials and genetic factors without any aids from additional biochemicals and growth factors.
American Psychological Association (APA)
Yoon, Jeong-Kee& Kang, Mi-Lan& Park, Joo Hyun& Lee, Kyoung-Mi& Shin, Young Min& Lee, Jin Woo…[et al.]. 2018. Direct Control of Stem Cell Behavior Using Biomaterials and Genetic Factors. Stem Cells International،Vol. 2018, no. 2018, pp.1-17.
https://search.emarefa.net/detail/BIM-1213614
Modern Language Association (MLA)
Yoon, Jeong-Kee…[et al.]. Direct Control of Stem Cell Behavior Using Biomaterials and Genetic Factors. Stem Cells International No. 2018 (2018), pp.1-17.
https://search.emarefa.net/detail/BIM-1213614
American Medical Association (AMA)
Yoon, Jeong-Kee& Kang, Mi-Lan& Park, Joo Hyun& Lee, Kyoung-Mi& Shin, Young Min& Lee, Jin Woo…[et al.]. Direct Control of Stem Cell Behavior Using Biomaterials and Genetic Factors. Stem Cells International. 2018. Vol. 2018, no. 2018, pp.1-17.
https://search.emarefa.net/detail/BIM-1213614
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1213614