New Turns for High Efficiency Knock-In of Large DNA in Human Pluripotent Stem Cells

Joint Authors

Feng, Bo
He, Xiangjun
Li, Yin-Xiong

Source

Stem Cells International

Issue

Vol. 2018, Issue 2018 (31 Dec. 2018), pp.1-7, 7 p.

Publisher

Hindawi Publishing Corporation

Publication Date

2018-07-03

Country of Publication

Egypt

No. of Pages

7

Abstract EN

The groundbreaking CRISPR technology is revolutionizing biomedical research with its superior simplicity, high efficiency, and robust accuracy.

Recent technological advances by a coupling CRISPR system with various DNA repair mechanisms have further opened up new opportunities to overcome existing challenges in knocking-in foreign DNA in human pluripotent stem cells, including embryonic stem cells (ESC) and induced pluripotent stem cells (iPSC).

In this review, we summarized the very recent development of CRISPR-based knock-in strategies and discussed the results obtained as well as potential applications in human ESC and iPSC.

American Psychological Association (APA)

He, Xiangjun& Li, Yin-Xiong& Feng, Bo. 2018. New Turns for High Efficiency Knock-In of Large DNA in Human Pluripotent Stem Cells. Stem Cells International،Vol. 2018, no. 2018, pp.1-7.
https://search.emarefa.net/detail/BIM-1213684

Modern Language Association (MLA)

He, Xiangjun…[et al.]. New Turns for High Efficiency Knock-In of Large DNA in Human Pluripotent Stem Cells. Stem Cells International No. 2018 (2018), pp.1-7.
https://search.emarefa.net/detail/BIM-1213684

American Medical Association (AMA)

He, Xiangjun& Li, Yin-Xiong& Feng, Bo. New Turns for High Efficiency Knock-In of Large DNA in Human Pluripotent Stem Cells. Stem Cells International. 2018. Vol. 2018, no. 2018, pp.1-7.
https://search.emarefa.net/detail/BIM-1213684

Data Type

Journal Articles

Language

English

Notes

Includes bibliographical references

Record ID

BIM-1213684