Insights into Endothelial Progenitor Cells: Origin, Classification, Potentials, and Prospects
Joint Authors
Kwong, Dora Lai Wan
Zhang, C. F.
Chopra, H.
Hung, M. K.
Pow, Edmond Ho Nang
Source
Issue
Vol. 2018, Issue 2018 (31 Dec. 2018), pp.1-24, 24 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2018-11-18
Country of Publication
Egypt
No. of Pages
24
Abstract EN
With the discovery of endothelial progenitor cells (EPCs) in the late 1990s, a paradigm shift in the concept of neoangiogenesis occurred.
The identification of circulating EPCs in peripheral blood marked the beginning of a new era with enormous potential in the rapidly transforming regenerative field.
Overwhelmed with the revelation, researchers across the globe focused on isolating, defining, and interpreting the role of EPCs in various physiological and pathological conditions.
Consequently, controversies emerged regarding the isolation techniques and classification of EPCs.
Nevertheless, the potential of using EPCs in tissue engineering as an angiogenic source has been extensively explored.
Concomitantly, the impact of EPCs on various diseases, such as diabetes, cancer, and cardiovascular diseases, has been studied.
Within the limitations of the current knowledge, this review attempts to delineate the concept of EPCs in a sequential manner from the speculative history to a definitive presence (origin, sources of EPCs, isolation, and identification) and significance of these EPCs.
Additionally, this review is aimed at serving as a guide for investigators, identifying potential research gaps, and summarizing our current and future prospects regarding EPCs.
American Psychological Association (APA)
Chopra, H.& Hung, M. K.& Kwong, Dora Lai Wan& Zhang, C. F.& Pow, Edmond Ho Nang. 2018. Insights into Endothelial Progenitor Cells: Origin, Classification, Potentials, and Prospects. Stem Cells International،Vol. 2018, no. 2018, pp.1-24.
https://search.emarefa.net/detail/BIM-1213741
Modern Language Association (MLA)
Chopra, H.…[et al.]. Insights into Endothelial Progenitor Cells: Origin, Classification, Potentials, and Prospects. Stem Cells International No. 2018 (2018), pp.1-24.
https://search.emarefa.net/detail/BIM-1213741
American Medical Association (AMA)
Chopra, H.& Hung, M. K.& Kwong, Dora Lai Wan& Zhang, C. F.& Pow, Edmond Ho Nang. Insights into Endothelial Progenitor Cells: Origin, Classification, Potentials, and Prospects. Stem Cells International. 2018. Vol. 2018, no. 2018, pp.1-24.
https://search.emarefa.net/detail/BIM-1213741
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1213741