Quality of Chronic Anticoagulation Control in Patients with Intracranial Haemorrhage due to Vitamin K Antagonists
Joint Authors
DeFelipe-Mimbrera, Alicia
Masjuan, Jaime
Estevez-Fraga, Carlos
Molina-Sanchez, Maria
Alvarez-Velasco, Rodrigo
Agüero-Rabes, Pablo
Crespo-Araico, Leticia
Viedma-Guiard, Elena
Cruz, Antonio
Vera, Rocío
Matute, Consuelo
Source
Issue
Vol. 2018, Issue 2018 (31 Dec. 2018), pp.1-6, 6 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2018-08-02
Country of Publication
Egypt
No. of Pages
6
Main Subjects
Abstract EN
Introduction.
Patients treated with vitamin K antagonists (VKA) are at increased risk of intracranial haemorrhage (ICH).
The purpose of our study was to determine the quality of previous anticoagulation control in patients with VKA-associated ICH.
Materials and Methods.
We prospectively assessed every consecutive patient admitted to our stroke unit with VKA-associated ICH between 2013 and 2016.
Demographic, clinical, and radiological variables, as well as consecutive international normalized ratios (INR) during 7 previous months, were extracted.
Time in therapeutic range (TTR), time over range (TOR), time below range (TBR), and percentage of INR within range (PINRR) were calculated.
Results and Discussion.
The study population comprised 53 patients.
Mean age was 79 years; 42% were women.
Forty-eight patients had atrial fibrillation (AF) and 5 mechanical prosthetic valves.
Therapeutic or infratherapeutic INR on arrival was detected in 64.4% of patients (95% CI 2.7 to 3.2).
TTR was 67.8% (95% CI: 60.2 to 75.6 %) and PINRR was 75% (95% CI: 49.9-100).
TOR was 17.2% (95% CI: 10.4 to 23.9% ) and TBR was 17% (95% CI: 10.6 to 23.9%).
Conclusion.
VKA-associated ICH happens usually in the context of good chronic anticoagulation control.
Newer risk assessment methods are required.
American Psychological Association (APA)
Estevez-Fraga, Carlos& Molina-Sanchez, Maria& Alvarez-Velasco, Rodrigo& Agüero-Rabes, Pablo& Crespo-Araico, Leticia& Viedma-Guiard, Elena…[et al.]. 2018. Quality of Chronic Anticoagulation Control in Patients with Intracranial Haemorrhage due to Vitamin K Antagonists. Stroke Research and Treatment،Vol. 2018, no. 2018, pp.1-6.
https://search.emarefa.net/detail/BIM-1214849
Modern Language Association (MLA)
Estevez-Fraga, Carlos…[et al.]. Quality of Chronic Anticoagulation Control in Patients with Intracranial Haemorrhage due to Vitamin K Antagonists. Stroke Research and Treatment No. 2018 (2018), pp.1-6.
https://search.emarefa.net/detail/BIM-1214849
American Medical Association (AMA)
Estevez-Fraga, Carlos& Molina-Sanchez, Maria& Alvarez-Velasco, Rodrigo& Agüero-Rabes, Pablo& Crespo-Araico, Leticia& Viedma-Guiard, Elena…[et al.]. Quality of Chronic Anticoagulation Control in Patients with Intracranial Haemorrhage due to Vitamin K Antagonists. Stroke Research and Treatment. 2018. Vol. 2018, no. 2018, pp.1-6.
https://search.emarefa.net/detail/BIM-1214849
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1214849