Stroke Outcome and Determinants among Patients with and without Diabetes in a Tertiary Hospital in Ghana
Joint Authors
Yorke, Ernest
Atiase, Yacoba
Akpalu, Josephine
Yawson, Alfred E.
Osei-Poku, Foster
Adjei, Patrick
Nkromah, Kodwo
Akpalu, Albert
Source
Issue
Vol. 2018, Issue 2018 (31 Dec. 2018), pp.1-9, 9 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2018-09-12
Country of Publication
Egypt
No. of Pages
9
Main Subjects
Abstract EN
Background.
Diabetes mellitus, a well-established independent risk factor for stroke, has varied association with stroke outcome from previous studies.
This study investigated stroke outcome and determinants among patients with and without diabetes in a tertiary hospital in Ghana.
Methods.
A prospective study conducted among stroke patients with and without diabetes admitted in a Ghanaian tertiary hospital.
Baseline clinical and biochemical data were documented.
Functional stroke outcome was evaluated at 1, 3, and 6 months after stroke using the modified Rankin Scale.
Results.
Number of participants enrolled were 326 and 105 (32.20%) had diabetes.
Higher proportions of diabetes patients had poor functional stroke outcome at 1, 3, and 6 months (79%, 75.23%, 73.33%) compared with those without diabetes (70.13%, 65.16, 61.99) (p>0.05).
Stroke patients with diabetes had lower survival compared with those without diabetes (p=0.0745).
Mortality at 6 months was more likely among ischaemic stroke patients with diabetes compared with those without diabetes (Odds Ratio 2.037; CI: 1.058-3.923).
Determinants of poor functional stroke outcome for diabetes patients were older age (Adjusted Odds Ratio (AOR)-1.07; CI-1.03-1.12), female gender (AOR-3.74; CI-1.26-12.65), and pneumonia (AOR-11.32; CI-1.93-220.05) whereas the determinants for those without diabetes were unemployment (AOR-4.19; CI-1.24-19.50), speech abnormalities (AOR-1.99; CI1.08-3.73), and pneumonia (AOR-4.05; CI-1.83-9.77).
High fasting plasma glucose (HR-1.15; CI-1.07-1.23), elevated temperature (HR-1.41; CI-1.11-1.79), and pneumonia (HR-2.25; CI-1.44-3.50) were determinants of low survival among all stroke patients.
Conclusion.
Trends towards poorer functional outcome and reduced survival were found among Ghanaian stroke patients with diabetes compared with those without diabetes.
Older age, female gender, pneumonia, elevated temperature, and fasting plasma glucose were determinants of adverse outcome in stroke patients with diabetes.
American Psychological Association (APA)
Akpalu, Josephine& Yawson, Alfred E.& Osei-Poku, Foster& Atiase, Yacoba& Yorke, Ernest& Adjei, Patrick…[et al.]. 2018. Stroke Outcome and Determinants among Patients with and without Diabetes in a Tertiary Hospital in Ghana. Stroke Research and Treatment،Vol. 2018, no. 2018, pp.1-9.
https://search.emarefa.net/detail/BIM-1214859
Modern Language Association (MLA)
Akpalu, Josephine…[et al.]. Stroke Outcome and Determinants among Patients with and without Diabetes in a Tertiary Hospital in Ghana. Stroke Research and Treatment No. 2018 (2018), pp.1-9.
https://search.emarefa.net/detail/BIM-1214859
American Medical Association (AMA)
Akpalu, Josephine& Yawson, Alfred E.& Osei-Poku, Foster& Atiase, Yacoba& Yorke, Ernest& Adjei, Patrick…[et al.]. Stroke Outcome and Determinants among Patients with and without Diabetes in a Tertiary Hospital in Ghana. Stroke Research and Treatment. 2018. Vol. 2018, no. 2018, pp.1-9.
https://search.emarefa.net/detail/BIM-1214859
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1214859