Chemoprotective activity of 3-indolylmethyl glucosinolate on induced gastric mucosal injury in male rats
Other Title(s)
النشاط الكيميائي الوقائي لثلاثي-إندوليل ميثيل الجلوكوزينولات على إصابة الغشاء المخاطي للمعدة المحدثة في ذكور الجرذان
Joint Authors
al-Shilabi, Idah Miftah Abd al-Karim
Khalifah, Samah Abd al-Salam
Source
Journal of Pure and Applied Sciences
Issue
Vol. 18, Issue 2 (30 Jun. 2019), pp.46-53, 8 p.
Publisher
Publication Date
2019-06-30
Country of Publication
Libya
No. of Pages
8
Main Subjects
Abstract EN
Mucosal damage in stomach therapy faces a major drawback in modern days due to the unpredictable side effects of the long-term uses of commercially available drugs.
The aim of the present investigation study is to evaluate the chemoprotective activities of 3-indolylmethyl glucosinolate against aspirin-induced gastric mucosal damage in male albino rats.
Rats were divided into two large groups, control group and ulcerated group.
Aspirin (500 mg/kg/body weight for a week), and followed by the beginning of different experimental regimens for a total experimental duration of one month.
Results of the present work showed that, the groups were treated with 3-indolylmethyl glucosinolate possessed protective activity by an increase the mucus level, protein granules and a great number of proliferation cells in the stomach.
So this study suggests that, 3-indolylmethyl glucosinolate possesses significant gastroprotective and antioxidant activities against aspirin-induced gastric ulcer in male albino rats.
American Psychological Association (APA)
al-Shilabi, Idah Miftah Abd al-Karim& Khalifah, Samah Abd al-Salam. 2019. Chemoprotective activity of 3-indolylmethyl glucosinolate on induced gastric mucosal injury in male rats. Journal of Pure and Applied Sciences،Vol. 18, no. 2, pp.46-53.
https://search.emarefa.net/detail/BIM-1215199
Modern Language Association (MLA)
al-Shilabi, Idah Miftah Abd al-Karim& Khalifah, Samah Abd al-Salam. Chemoprotective activity of 3-indolylmethyl glucosinolate on induced gastric mucosal injury in male rats. Journal of Pure and Applied Sciences Vol. 18, no. 2 (2019), pp.46-53.
https://search.emarefa.net/detail/BIM-1215199
American Medical Association (AMA)
al-Shilabi, Idah Miftah Abd al-Karim& Khalifah, Samah Abd al-Salam. Chemoprotective activity of 3-indolylmethyl glucosinolate on induced gastric mucosal injury in male rats. Journal of Pure and Applied Sciences. 2019. Vol. 18, no. 2, pp.46-53.
https://search.emarefa.net/detail/BIM-1215199
Data Type
Journal Articles
Language
English
Notes
Record ID
BIM-1215199