Factors Affecting Inpatient Mortality in Elderly People with Acute Kidney Injury
Joint Authors
Tan, Jackson
Awan, Safia
Azmat, Rabeea
Naseer, Nazish
Khalil, Muhammad Ashhad Ullah
Khalil, Muhammad Abdul Mabood
Source
Issue
Vol. 2018, Issue 2018 (31 Dec. 2018), pp.1-6, 6 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2018-05-06
Country of Publication
Egypt
No. of Pages
6
Main Subjects
Medicine
Information Technology and Computer Science
Abstract EN
Background.
Acute Kidney Injury (AKI) is common in elderly people (EP).
There is paucity of data on predictor of mortality in EP with AKI.
Objective.
This study was done to know more about factors associated with inpatient mortality in EP with AKI.
Methods.
We retrospectively reviewed medical records of patients aged 65 years or above hospitalized with a diagnosis of AKI at Aga Khan University Hospital, Karachi, between January 2005 and December 2010.
Binary logistic regression models were constructed to identify factors associated with mortality in EP with AKI.
Results.
431 patients had AKI, with 341 (79.1%) having stage I AKI, 56 (13%) having stage II AKI, and 34 (7.9%) having stage III AKI.
Out of 431 patients, 142 (32.9%) died.
Mortality increased with increasing severity of AKI.
Mortality was 50% (17/34) in AKI stage III, 44.6% (25/56) in AKI stage II, and 29.3% (100/341) in AKI stage I.
Factors associated with increased inpatients mortality were presence of stage III AKI (OR: 3.20, P=0.04, 95% CI: 1.05–9.72), presence of oliguria (OR: 3.42, P=0.006, 95% CI: 1.42–8.22), and need for vasopressors (OR: 6.90, P<0.001, 95% CI: 2.42–19.65).
Median bicarbonate 18 versus 17 between those who survived and those who died was associated with less mortality (OR: 0.94, P=0.02, 95% CI: 0.89–0.99).
History of hypertension (OR: 0.49, P=0.03, 95% CI: 0.25–0.95) and high admission creatinine (OR: 0.68, P=0.01, 95% CI: 0.50–0.91) were also associated with less mortality.
Conclusion.
Mortality in EP increases with increasing severity of AKI.
Presence of stage III AKI, oliguria, and hemodynamic instability needing vasopressor are associated with increased mortality.
Increased median bicarbonate, presence of hypertension, and high admission creatinine were various factors associated with decreased inpatient mortality.
Increasing age and need for dialysis did not increase mortality in elderly population.
American Psychological Association (APA)
Khalil, Muhammad Abdul Mabood& Awan, Safia& Azmat, Rabeea& Khalil, Muhammad Ashhad Ullah& Naseer, Nazish& Tan, Jackson. 2018. Factors Affecting Inpatient Mortality in Elderly People with Acute Kidney Injury. The Scientific World Journal،Vol. 2018, no. 2018, pp.1-6.
https://search.emarefa.net/detail/BIM-1215606
Modern Language Association (MLA)
Khalil, Muhammad Abdul Mabood…[et al.]. Factors Affecting Inpatient Mortality in Elderly People with Acute Kidney Injury. The Scientific World Journal No. 2018 (2018), pp.1-6.
https://search.emarefa.net/detail/BIM-1215606
American Medical Association (AMA)
Khalil, Muhammad Abdul Mabood& Awan, Safia& Azmat, Rabeea& Khalil, Muhammad Ashhad Ullah& Naseer, Nazish& Tan, Jackson. Factors Affecting Inpatient Mortality in Elderly People with Acute Kidney Injury. The Scientific World Journal. 2018. Vol. 2018, no. 2018, pp.1-6.
https://search.emarefa.net/detail/BIM-1215606
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1215606