Effect of sertraline and fluoxetine on the reproductive abilities of male rats Rattus norvegicus
Joint Authors
Husayn, Ali Mani
Madlul, Zaman Subhi
Faris, Sattar Abbud
Source
Issue
Vol. 7, Issue 1 (30 Jun. 2019), pp.26-32, 7 p.
Publisher
University of Thi-Qar College of Science
Publication Date
2019-06-30
Country of Publication
Iraq
No. of Pages
7
Main Subjects
Abstract EN
The present study was designed to know the effect of sertraline and fluoxetine on the reproductive abilities of male rats.
The experiment consisted of five groups (each group contains of 5 males), the first (control) group was injected (I.P) with 0.25ml of normal saline, the second group was injected with sertraline (10 mg / kg), the third group was injected with sertraline (20 mg / kg), the fourth group was injected with fluoxetine (5 mg / kg) and the fifth group was injected with fluoxetine (10 mg / kg).
.The results showed a significant decrease (P≤0.05) in the number of sperms and in the level of testosterone hormone and a significant increase (P≤0.05) in the percentage of sperm deformities in all treated groups when compared with control group.
The histologically examination showed that there was changes in the testis including the dissociation of the connective tissue in second and fifth groups, decrease in the number of spermatgonia, and Leydig cells, bloody congestion in third and fifth groups, hemorrhage and necrosis in forth group.
American Psychological Association (APA)
Madlul, Zaman Subhi& Faris, Sattar Abbud& Husayn, Ali Mani. 2019. Effect of sertraline and fluoxetine on the reproductive abilities of male rats Rattus norvegicus. Journal of Thi-Qar Science،Vol. 7, no. 1, pp.26-32.
https://search.emarefa.net/detail/BIM-1217375
Modern Language Association (MLA)
Madlul, Zaman Subhi…[et al.]. Effect of sertraline and fluoxetine on the reproductive abilities of male rats Rattus norvegicus. Journal of Thi-Qar Science Vol. 7, no. 1 (Jun. 2019), pp.26-32.
https://search.emarefa.net/detail/BIM-1217375
American Medical Association (AMA)
Madlul, Zaman Subhi& Faris, Sattar Abbud& Husayn, Ali Mani. Effect of sertraline and fluoxetine on the reproductive abilities of male rats Rattus norvegicus. Journal of Thi-Qar Science. 2019. Vol. 7, no. 1, pp.26-32.
https://search.emarefa.net/detail/BIM-1217375
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references : p. 30-32
Record ID
BIM-1217375