تأثير الأميجدالين في كل من نسيجي القلب و الرئة، و ذلك على عينة من الهامستر السوري : دراسة نسيجية

Abstract EN

and aim of the study: According to the increasing incidence of cancers worldwide, and the wildly use of complementary and alternative medicine (CAM) as one of the treatment choices, researches are concerning in studying CAM and its pathways and side effects.

Amygdalin is one of these methods.

Many researches are considering it role in treatment of many diseases, especially cancers.

This histological study was built to detect the role of this drug on the main vital tissues, lung and heart in Hamsters to define any toxic side effects during interpretoneal injection.

Materials and methods: a sample of 15 hamsters were incubated.

Amygdaline was injected interpretonial daily for 10 days.

Hamsters were sacrificed sequentially (after 5,10 days).

Lung and heart were prepared for the histological study.

Results: Qui square test showed no statistic significance using qui square test, between frequencies of normal lung and lung with interstitial pneumonia (P=0.070) within 10 days.

there was no statistic significance, between frequencies of normal heart and injured heart in 5 or 10 days.

Conclusions: No toxic effects were detected in the heart tissue, while there were an interstitial pneumonia in the lung tissue samples.