Toxicity of apricot seeds extracts as a rodenticide for climb rats Rattus rattus (Rodentia : Muridae)‎

Abstract EN

This study investigated the efficacy of the apricot seeds extracts in Rattus rattus L.

(Rodentia: Muridae).

The used of 28 rats has been selected to study acute and chronic toxicity to start a trial in the non-choice test.

three animals for each of acetone, ethanol, hot water, cold water extract , and powder seeds.

Five animals were used for hexane extract twice LD50 apricot seeds crushed maize bait and seven animals were used for LD50 apricot seeds hexane extract crushed maize bait.

The concentration used for LD50 and twice LD50 were calculated 2.14 and 4.28%, respectively.

The experiment in a non-choice laboratory test, results indicated for an experiment that LD50 of hexane apricot seeds extract highest toxicity treatment after 48 hrs was recorded 71.43% and acceptability 48.87%, twice LD50 of apricot seeds hexane extract bait recorded mortality 60% and acceptability 41.47%.

The most acceptable bait was cold water apricot extract recorded 92.76%.

Histopathological changes after 28 days for twice hexane extract and seeds powder in kidney showing membranoproliferative glomerulonephritis and the renal tubules some renal tubules showing costs, liver showing widely dilated hepatic sinusoids, ballooning degeneration and disorganization of hepatocytes.

Testis showing undulation and buckling of basal laminae of the seminiferous tubules, there is maturation arrest at various stages of spermatogenesis.

Ovary showing without any cellular content and atrophied.