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Effect of branched chain amino acid supplementation on dialysis adequacy and nutritional parameters in hemodialysis patients
Joint Authors
Abu Zayd, Samih
Rabi, Ahmad
al-Rifai, Fatimah A.
Sharif, Nifin
Source
Saudi Journal of Kidney Diseases and Transplantation
Issue
Vol. 31, Issue 6 (31 Dec. 2020), pp.1361-1365, 5 p.
Publisher
Saudi Center for Organ Transplantation
Publication Date
2020-12-31
Country of Publication
Saudi Arabia
No. of Pages
5
Main Subjects
Abstract EN
Malnutrition in hemodialysis (HD) patients is caused by deficient nutrient and protein intake and has a negative impact on patient outcomes.
The assessment of dialysis adequacy in these patients depends to a large extent on the calculation of urea clearance using dialyzer clearance of urea (K) multiplied by the duration of the dialysis treatment (t, in minutes) divided by the volume of distribution of urea in the body (V, in mL); Kt/V.
This study aims to detect the effect of branched-chain amino acid (BCAA) supplementation on Kt/V and other nutritional parameters such as serum albumin as well as body mass index.
Forty-six patients from the HD Unit of Mostafa Mahmoud Hospital were included in this study.
Daily intake of BCAA was continued for three months.
At the start of the study, before the intervention, and at the end of the 3 rd month, we measured serum albumin, valine, leucine, iso-leucine, and Kt/V.
Analysis of data was performed using paired and independent t-test.
We found that BCAA has a highly significant effect on increasing the level of albumin, leucine, isoleucine, valine, and Kt/V in HD patients (P <0.001) (Paired t-test).
BCAA supplements could be used in this patient population to improve dialysis adequacy and outcome.
American Psychological Association (APA)
Abu Zayd, Samih& Rabi, Ahmad& al-Rifai, Fatimah A.& Sharif, Nifin. 2020. Effect of branched chain amino acid supplementation on dialysis adequacy and nutritional parameters in hemodialysis patients. Saudi Journal of Kidney Diseases and Transplantation،Vol. 31, no. 6, pp.1361-1365.
https://search.emarefa.net/detail/BIM-1243177
Modern Language Association (MLA)
Abu Zayd, Samih…[et al.]. Effect of branched chain amino acid supplementation on dialysis adequacy and nutritional parameters in hemodialysis patients. Saudi Journal of Kidney Diseases and Transplantation Vol. 31, no. 6 (Nov. / Dec. 2020), pp.1361-1365.
https://search.emarefa.net/detail/BIM-1243177
American Medical Association (AMA)
Abu Zayd, Samih& Rabi, Ahmad& al-Rifai, Fatimah A.& Sharif, Nifin. Effect of branched chain amino acid supplementation on dialysis adequacy and nutritional parameters in hemodialysis patients. Saudi Journal of Kidney Diseases and Transplantation. 2020. Vol. 31, no. 6, pp.1361-1365.
https://search.emarefa.net/detail/BIM-1243177
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references : p. 1364-1365
Record ID
BIM-1243177