Rare renal pathologic manifestation of antineutrophil cytoplasmic antibodies associated vasculitis as suppurative interstitial nephritis : a case report and review of the literature
Joint Authors
Acikalin, Mustafa Fuat
Ozkurt, Sultan
Mengus, Cigdem
Bilge, Nazife Sule Yasar
Yalcin, Ahmet Ugur
Source
Saudi Journal of Kidney Diseases and Transplantation
Issue
Vol. 31, Issue 6 (31 Dec. 2020), pp.1420-1426, 7 p.
Publisher
Saudi Center for Organ Transplantation
Publication Date
2020-12-31
Country of Publication
Saudi Arabia
No. of Pages
7
Main Subjects
Abstract EN
A 69-year old male patient attended our clinic with fatigue, fever, anuria, nephritic syndrome and severe renal failure.
Kidney biopsy showed pauci-immune crescentic glomerulonephritis with an unusual association of suppurative interstitial nephritis.
Though most patients with renal involvement linked to antineutrophil cytoplasmic antibodies associated vasculitis (AAV) have pauci-immune glomerulonephritis, only a few patients were identified to have atypical renal pathology.
In most cases, mononuclear tubulointerstitial infiltrate may be a feature of AAV, suppurative interstitial nephritis is very rare.
In the literature, we found only one case reported associated with suppurative interstitial nephritis without glomerulonephritis who later developed classic pauci-immune necrotizing glomerulonephritis.
Here, we report a case diagnosed as AAV, presenting with pauci-immune crescentic glomerulonephritis and suppurative interstitial nephritis.
It is not clear whether suppurative interstitial nephritis is a severe disease variant in AAV-associated renal disease.
As described in the first case the lack of improvement in renal functions in spite of intense immunosuppressive treatment leads to the conclusion that suppurative interstitial nephritis is a marker of poor prognosis.
American Psychological Association (APA)
Ozkurt, Sultan& Acikalin, Mustafa Fuat& Mengus, Cigdem& Bilge, Nazife Sule Yasar& Yalcin, Ahmet Ugur. 2020. Rare renal pathologic manifestation of antineutrophil cytoplasmic antibodies associated vasculitis as suppurative interstitial nephritis : a case report and review of the literature. Saudi Journal of Kidney Diseases and Transplantation،Vol. 31, no. 6, pp.1420-1426.
https://search.emarefa.net/detail/BIM-1247393
Modern Language Association (MLA)
Acikalin, Mustafa Fuat…[et al.]. Rare renal pathologic manifestation of antineutrophil cytoplasmic antibodies associated vasculitis as suppurative interstitial nephritis : a case report and review of the literature. Saudi Journal of Kidney Diseases and Transplantation Vol. 31, no. 6 (Nov. / Dec. 2020), pp.1420-1426.
https://search.emarefa.net/detail/BIM-1247393
American Medical Association (AMA)
Ozkurt, Sultan& Acikalin, Mustafa Fuat& Mengus, Cigdem& Bilge, Nazife Sule Yasar& Yalcin, Ahmet Ugur. Rare renal pathologic manifestation of antineutrophil cytoplasmic antibodies associated vasculitis as suppurative interstitial nephritis : a case report and review of the literature. Saudi Journal of Kidney Diseases and Transplantation. 2020. Vol. 31, no. 6, pp.1420-1426.
https://search.emarefa.net/detail/BIM-1247393
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references : p. 1425-1426
Record ID
BIM-1247393