Lethal midline granuloma importance of early diagnosis : a case report

Abstract EN

Non-Hodgkin’s lymphomas of the sinonasal region are uncommon.

They are included in the so-called non-healing midline granuloma syndrome, which is characterized by slowly progressive deep midfacial destruction of soft tissue, cartilage, and bone.

Many terms have been used in the literature such as malignant reticulosis or polymorphic reticulosis.

A case of high-grade lymphoma is reported, and it is diagnosed in a very late stage as it was mistaken for inflammatory disease and treated medically for several months as a dacryocystitis.

When appropriately diagnosed a combined radioand chemotherapy was offered to the patient, but follow up of patient revealed that he was died at home after 3 weeks of treatment.