Ashwagandha (Withania Somnifera) and their effects on the reproductive hormones of male rats
Other Title(s)
الأشواجندا و تأثيرها على الهرمونات التناسلية لذكور الجرذان
Author
Source
Issue
Vol. 37, Issue 2 (31 Dec. 2021), pp.1-22, 22 p.
Publisher
The Egyptian Home Economics Association
Publication Date
2021-12-31
Country of Publication
Egypt
No. of Pages
22
Main Subjects
Topics
- Penal functions
- Medical examinations
- Analytical chemistry
- Feeds
- Valproic acid
- Withania
- Weight gain
- Body weight
Abstract AR
العربي
Abstract EN
Effect of Ashwagandha (powder, extract and their mixtures) on feed intake, body weight gains, feed efficiency ratio, lipid profile, liver enzymes, kidney functions and fertility hormones in rats were examined.
Forty-two adult male rats weighing (115±5 g) were divided into 2 main groups.
The first main group fed on basal diet as a (negative control group) consisted of (7) rats, while the second main group consisted of (35) rats divided into five similar subgroups were injected with sodium valproate to induce testicular injury at a dose (500 mg/kg) body weight.
The first subgroup was then maintained as positive control (+Ve), the second subgroup was fed on basal diet plus Ashwagandha powder (100 g/kg diet), the third subgroup was fed on basal diet plus Ashwagandha extract (10 mg/kg b.
w/rat) orally, the fourth subgroup was fed on basal diet plus L-carnitine (150 mg/kg b.
w/rat) orally, the fifth subgroup was fed on basal diet plus Ashwagandha powder and (Ashwagandha extract & L-carnitine/rat orally) for one month.
At the end of the experimental period, blood samples were collected from each rat and separate the serum which used for determination of some biochemical analysis.
Tests specimens were taken for examination.
The results of Ashwagandha powder, extract and combination orally to rats revealed that non-significant differences in body weight gains, feed efficiency ratio, feed intake and decreased serum lipid profile and increased in HDL-c.
It also decreased in liver enzymes, kidney functions and fertility hormones serum Testosterone, Follicle Stimulating Hormone, Lutenizing Hormone in induced rats which feed on combination of Ashwagandha powder, extract and L-carnitine.
So this study recommended using Ashwagandha in improving fertility for patients.
American Psychological Association (APA)
Ali, Hind Muhammad. 2021. Ashwagandha (Withania Somnifera) and their effects on the reproductive hormones of male rats. Home Economics Journal،Vol. 37, no. 2, pp.1-22.
https://search.emarefa.net/detail/BIM-1255306
Modern Language Association (MLA)
Ali, Hind Muhammad. Ashwagandha (Withania Somnifera) and their effects on the reproductive hormones of male rats. Home Economics Journal Vol. 37, no. 2 (Dec. 2021), pp.1-22.
https://search.emarefa.net/detail/BIM-1255306
American Medical Association (AMA)
Ali, Hind Muhammad. Ashwagandha (Withania Somnifera) and their effects on the reproductive hormones of male rats. Home Economics Journal. 2021. Vol. 37, no. 2, pp.1-22.
https://search.emarefa.net/detail/BIM-1255306
Data Type
Journal Articles
Language
English
Notes
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Record ID
BIM-1255306