Effect of mango and banana peels induced on toxicity by lead acetate in rats

Abstract EN

This study was carried out to determine the effect of dry banana peels (Musa Acuminate) and dry mango peels (Mangifera indica L.

) against lead toxicity in weaning rats.

Forty five growing male albino rats with weighting (70 ± 5g), and were divided into two main groups.

The first group was the negative control group (9) rats, the second group (36) rats were exposed to lead acetate (200 mg/ kg from weight rat) daily drinking orally and divided into four subgroups.

The subgroup one positive control group fed on basal diet only, the subgroup two fed on basal diet fortified with (15% ) banana peels, the subgroup three fed on basal diet fortified with (15% ) mango peels, the subgroup four fed on basal diet fortified with (15% ) combination of (banana and mango peels) for (6) weeks.

Blood samples were collected and hemoglobin was determined, then iron, lead, liver enzymes and kidney function were estimated.

Calcium, phosphorus and lead were also evaluated in the bones.

The best result found in the group fed on basal diet fortified with (15% ) combination banana and mango peels improved daily feed intake, body weight gain; feed efficiency ratio, hemoglobin and serum iron level.

Moreover, lead concentration was decreased in serum and also it was improved the concentration of calcium, phosphorous as well as lead in bone of intoxicated rats.

Dry peels of fruits were improved liver enzymes and kidney functions compared with positive group.

The histopathology results were agreedwith the results of serum parameters.

These results recommend increasing the consumption of banana and mango peels.

Nutrition Education Programs are needed to illustrate the importance of banana and mango peels in reducing lead toxicity.