Synthesis and biological evaluation of some pyrrolidine-2-one derivatives
Joint Authors
Bayti, Nadiyah Aziz
Husayn, Rida Ib.
Kazim, Sahar Ab
Source
al-Mustansiriyah Journal of Science
Issue
Vol. 31, Issue 1 (31 Mar. 2020), pp.31-40, 10 p.
Publisher
al-Mustansyriah University College of Science
Publication Date
2020-03-31
Country of Publication
Iraq
No. of Pages
10
Main Subjects
Topics
Abstract EN
In this research a number of pyrrolidine-2-one derivatives were prepared by lactamization of γ –butyrolactone (GBL) with hydrazine hydrate (80% ) to produce (1-aminopyrrolidine-2-one) that undergoes several reactions to afford these derivatives that diagnosed by infrared, nuclear magnetic resonance and mass spectroscopy.
Antibacterial activity has also been studied using some types of bacteria, some were found to have good antibacterial In this research a number of pyrrolidine-2-one derivatives were prepared by lactamization of γ –butyrolactone (GBL) with hydrazine hydrate (80% ) to produce (1-aminopyrrolidine-2-one) that undergoes several reactions to afford these derivatives that diagnosed by infrared, nuclear magnetic resonance and mass spectroscopy.
Antibacterial activity has also been studied using some types of bacteria, some were found to have good antibacterial activity.
American Psychological Association (APA)
Bayti, Nadiyah Aziz& Husayn, Rida Ib.& Kazim, Sahar Ab. 2020. Synthesis and biological evaluation of some pyrrolidine-2-one derivatives. al-Mustansiriyah Journal of Science،Vol. 31, no. 1, pp.31-40.
https://search.emarefa.net/detail/BIM-1268888
Modern Language Association (MLA)
Bayti, Nadiyah Aziz…[et al.]. Synthesis and biological evaluation of some pyrrolidine-2-one derivatives. al-Mustansiriyah Journal of Science Vol. 31, no. 1 (2020), pp.31-40.
https://search.emarefa.net/detail/BIM-1268888
American Medical Association (AMA)
Bayti, Nadiyah Aziz& Husayn, Rida Ib.& Kazim, Sahar Ab. Synthesis and biological evaluation of some pyrrolidine-2-one derivatives. al-Mustansiriyah Journal of Science. 2020. Vol. 31, no. 1, pp.31-40.
https://search.emarefa.net/detail/BIM-1268888
Data Type
Journal Articles
Language
English
Notes
-
Record ID
BIM-1268888