Phytoconstituents, antioxidant and inhibitory activity against α-amylase and α-glucosidase of Opuntia ficus-indica
Other Title(s)
المكونات النباتية و مضادات الأكسدة و النشاط المثبط لأنزيمات ألفا-اميلاز و ألفا-جلوكوسيداز لنبات الصبر
Joint Authors
Jaradat, Nidal
Rabi, Lamis
al-Tamimi, Muhammad
Source
An-Najah University Journal for Research-A : Natural Sciences
Issue
Vol. 34, Issue 1 (29 Feb. 2020), pp.31-48, 18 p.
Publisher
An-Najah National University Deanship of Scientific Research
Publication Date
2020-02-29
Country of Publication
Palestine (West Bank)
No. of Pages
18
Main Subjects
Abstract EN
Hyperglycemia and oxidative stress are associated with type 2 diabe-tes mellitus.
The aim of this study is to evaluate the antioxidant, anti α-amylase and α-glucosidase activities of Opuntia ficus-indica cladodes and fruit juice.
Four extracts of Opuntia ficus-indica cladodes were used, while fruit juice was only freeze-dried.
Phytochemicals were determined of each extract and each extract was in-vitro evaluated for free radical scavenging, α-amylase and α-glucosidase inhibitory activities.
Opuntia ficus-indica cladodes methanol extract has the highest contentin flavonoid, phenols and alkaloids and it also has the highest antioxidant capacity with IC50 value 6.16±0.59 μg/ml; compared to Trolox’s IC50value 2.09±1.7μg/ml.
For α-amylase inhibitory effect aqueous extract was the most potent with IC50 value 16.98±0.77μg/ml followed by acetone extract with IC50 value 25.11±0.89μg/ml.
All extracts showed inhibitory activity with different extent against α-glucosidase enzyme, the aqueous extract showed the most potent activity followed by acetone extract.
American Psychological Association (APA)
Rabi, Lamis& al-Tamimi, Muhammad& Jaradat, Nidal. 2020. Phytoconstituents, antioxidant and inhibitory activity against α-amylase and α-glucosidase of Opuntia ficus-indica. An-Najah University Journal for Research-A : Natural Sciences،Vol. 34, no. 1, pp.31-48.
https://search.emarefa.net/detail/BIM-1275894
Modern Language Association (MLA)
Rabi, Lamis…[et al.]. Phytoconstituents, antioxidant and inhibitory activity against α-amylase and α-glucosidase of Opuntia ficus-indica. An-Najah University Journal for Research-A : Natural Sciences Vol. 34, no. 1 (Feb. 2020), pp.31-48.
https://search.emarefa.net/detail/BIM-1275894
American Medical Association (AMA)
Rabi, Lamis& al-Tamimi, Muhammad& Jaradat, Nidal. Phytoconstituents, antioxidant and inhibitory activity against α-amylase and α-glucosidase of Opuntia ficus-indica. An-Najah University Journal for Research-A : Natural Sciences. 2020. Vol. 34, no. 1, pp.31-48.
https://search.emarefa.net/detail/BIM-1275894
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references : p. 46-48
Record ID
BIM-1275894