Helicobacter pylori infection in adult patients with non-ulcer dyspepsia

Abstract EN

Non -ulcer dyspepsia is the most common reason for patients to experience chronic epigastric pain or discomfort in which the causes are multifactorial but Helicobacter pylori infection is widespread and well recognized as major cause of gastrointestinal diseases.

Aim: This study aimed to estimate prevalence of Helicobacter pylori infection among dyspeptic patients with no ulcer formation Method: The present cross - sectional study was done in the outpatients department of AL-Gomhoria Teaching Hospital.

A total of 208 adult patients attending Gastro - Intestinal Outpatient Department for upper gastrointestinal disorders symptoms.

To find out the Helicobacter pylori the patients were examined for stool antigen using Card test.

Negative upper endoscopy examination was required to rule out ulcer formation.

A detailed data was collected, regarding the sex, age of the patient and smoking habits Result: out of these 208 patients,92 were found positive for Helicobacter pylori by stool Ag test , giving a prevalence of (44.2%).

Among a total of 143 males, 61 were found positive for Helicobacter pylori (42.7%) and among 65 females, 31 were found positive (47.7%).

Age distribution showed maximum prevalence of Helicobacter pylori in the age group of 30-39 years (50.7%) with statistically significant p value 0.01 and minimum prevalence in the age group of more than 70 years (20%).

A higher prevalence of Helicobacter pylori was found among smoker patients (54.9%) with statistically significant p value 0.001 and among patients having gastritis (53.3%) was statistically significant p value 0.001.

The study of symptoms intensity showed a prevalence of (50%) in patients with severe symptoms intensity were p value was 0.0 1 statistically significant.

Conclusion: Dyspepsia with evidence of Helicobacter pylori infection and absence of ulcer formation were with highest prevalence among smoker cigarette, gastritis and those patients with age group of 30-39 years.