Synthesis of some imine, from pyrazole-1-carbaldehyde compound

Abstract EN

In this paper the synthesis of N[(1E)-1- ( 3, 5.

- disubstituted phenyl -4, 5-dihydro-1H- pyrazol-1- yl) ethylidene or methylidene] substituted aniline [13-15] [17-19] and 1, 1-{benzene- 1, 4- or -1, 3- diylbis [nitrilo (E) methylylidene]} bis( 4, 5- dihydro -1H- pyrazole -3, 5- disubstituted phenyl) [16, 20] is reported.

Substituted acetophenone was treated with substituted benzaldehyde to give chalcones ((2E)-1, 3- disubstituted phenyl prop-2-ene-1- one) [1-4], the chalcones was treated with hydrazine hydrate in the presence of formic or acetic acid ethanol to give 1-(3, 5.

-disubstituted phenyl-4, 5- dihydro-1H- pyrazol-1- yl) methanol or ethanone [5-12], then this products changed to imines through reaction with substituted aromatic aniline and sodium hydroxide in ethanol to give the substituted pyrazoles.

Also the substituted compounds [5-12] were converted to 1-{(1E)-1-[2-(2, 4-dinitrophenyl) hydrazinylidene] methyl or ethyl} – 4, 5- dihydro -1H- pyrazole-3, 5-disubstituted phenyl [21-28] by reaction with 2, 4-dinitrophenyl hydrazine in ethanol.

The synthetic compound's structure.

confirmed by IR.

, UV.

Spectra and.

physical method.