Study of the effect of feeding two cultivars of purslane (Portulaca Oleracea I.) on lipid profile and lipid peroxidation of adult male sprague dawley rats
Other Title(s)
دراسة تأثير إطعام نوعين من نبات البقلة على مستوى دهون الدم و فوق أكسدتها لذكورالجرذان من نوع سبراغ داولي
Joint Authors
al-Amiri, Hasan
Takruri, Hamid Rabah
Source
An-Najah University Journal for Research-A : Natural Sciences
Issue
Vol. 35, Issue 1 (28 Feb. 2021), pp.1-18, 18 p.
Publisher
An-Najah National University Deanship of Scientific Research
Publication Date
2021-02-28
Country of Publication
Palestine (West Bank)
No. of Pages
18
Main Subjects
Abstract EN
This study was conducted to evaluate the effect of feeding purslane on lipid profile and lipid peroxidation in adult male Sprague Dawley rats fed high cholesterol diet.
Wild and cultivated purslane were collected, dried and milled to be used in rat diets.
Forty male Sprague-Dawley rats at 9 weeks of age, weighing (200-250g) were randomly divided into four experimental groups, 10 rats each, and fed either normal diet (group 1) or high cholesterol diet (HCD) (1% cholesterol) (groups 2, 3 and 4) for 4 weeks, at the end of the fourth week, the prepared wild and cultivated purslane plants were administered at 2.5% to (groups 3 and 4, respectively) for another 8 weeks.
The addition of wild and cultivated purslane significantly lowered the serum cholesterol levels in groups 3 and 4 to 133.1 ± 34.5 and 130.9 ± 21.2 mg/dl, respectively, in comparison to HCD group without purslane (169.8 ± 57.9), and low- density lipoprotein (LDL) levels (96.3 ± 32.8 and 95.4 ± 20.1 mg/dl) in comparison to HCD group without purslane (132.5 ± 62.5).
Blood peroxidation (MDA) values in wild and cultivated purslane groups (10.9 ± 1.6 and 10.9 ± 2.8 nmol/ml) were significantly lower than the MDA level in groups 1 and 2 (14.3±3.0 and 15.8±5.0 nmol/ml respectively).
In conclusion, the addition of purslane to the diet of rats decreased serum cholesterol, LDL and lipid peroxidation levels indicating that the plant could have important medical implications.
American Psychological Association (APA)
al-Amiri, Hasan& Takruri, Hamid Rabah. 2021. Study of the effect of feeding two cultivars of purslane (Portulaca Oleracea I.) on lipid profile and lipid peroxidation of adult male sprague dawley rats. An-Najah University Journal for Research-A : Natural Sciences،Vol. 35, no. 1, pp.1-18.
https://search.emarefa.net/detail/BIM-1287148
Modern Language Association (MLA)
al-Amiri, Hasan& Takruri, Hamid Rabah. Study of the effect of feeding two cultivars of purslane (Portulaca Oleracea I.) on lipid profile and lipid peroxidation of adult male sprague dawley rats. An-Najah University Journal for Research-A : Natural Sciences Vol. 35, no. 1 (Feb. 2021), pp.1-18.
https://search.emarefa.net/detail/BIM-1287148
American Medical Association (AMA)
al-Amiri, Hasan& Takruri, Hamid Rabah. Study of the effect of feeding two cultivars of purslane (Portulaca Oleracea I.) on lipid profile and lipid peroxidation of adult male sprague dawley rats. An-Najah University Journal for Research-A : Natural Sciences. 2021. Vol. 35, no. 1, pp.1-18.
https://search.emarefa.net/detail/BIM-1287148
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references : p. 14-18
Record ID
BIM-1287148