The effect of hemodialysis on colloid osmotic pressure and intraocular pressure

Abstract EN

Objective : to investigate the relationship between changes in the intraocular pressure and plasma osmolarity, plasma colloid osmotic pressure, and body weight before and after hemodialysis.

Methods: Intraocular pressure, plasma osmolarity, plasma colloid osmotic pressure, and body weight were evaluated before and after hemodialysis in 32 patients with chronic renal failure.

Results: Significant decrease in intraocular pressure and plasma osmolarity was found post dialysis (p 0.00l).

Plasma colloid osmotic pressure increased significantly after dialysis (p 0.00l).

Because of fluid removal during dialysis body weight decreased significantly after dialysis (p < 0.001).

There was no significant correlation between the changes in intraocular pressure and that in plasma osmolarity (r = -0.2, p > 0.2).

Change in the intraocular pressure correlated with change in plasma colloid osmotic pressure (r = -0.5, p 0.00l) and the change in body weight (r = 0.5, p 0.00l).

The change in plasma colloid osmotic pressure and that in body weight was statistically significant (r = -0.7, p0.00l).

Conclusion : the decrease in intraocular pressure correlated inversely with the increase in colloid osmotic pressure because of fluid removal during hemodialysis.