Lipids profile reduction in rats fed (matthiola incana)‎ seed rich in omega-3 fatty acids

Abstract EN

The present study was designed to study the effect of Stock seeds, virgin coconut oil and sunflower oil on hyperlipidemic rats.

Forty adult male albino rats were used in this study, weighting (150±10g) were divided into eight groups, five rats each.

One of them was kept as a control –ve group, while the other seven groups were fed on the diet plus 1.5% cholesterol for 21 days Stock seeds powder added at percent 2.5% and 5% , virgin coconut and sunflower oil were added at percent 1% and 2% from the main diet.

Body weight gain, feed intake, feed efficiency ratio, serum lipid profiles (TG, TC, LDL-c, VLDL-c, HDL-c and AI), serum glucose, serum liver enzymes (ALT, AST and ALP), kidney functions (creatinine, uric acid and urea levels) and complete blood count (RBCs, WBCs, hemoglobin and platelet).

From the obtained results it could be concluded that feeding on of Stock seeds powder, virgin coconut oil and sunflower oil caused significant (P≤0.05) increase in HDL-c, RBCs and hemoglobin, but with significant (P ≤ 0.05) decreases weight gain and in the rest of the analyses as compared with control (+ve) group, and enhanced the kidney and liver functions with the decrease of ALT, AST, ALP, creatinine, uric acid, urea and serum glucose which reflects the powerful nutraceutical therapeutic effect for feeding on of Stock seeds, virgin coconut oil and sunflower oil for treatment hyperlipidemia in rats.